Action of terpenoids on energy metabolism

Knobloch, Karl; Weigand, H.; Weis, Norbert; Vigenschow, Helmut; Knobloch, J; Schwarm, Michael; Schwarm, H-M

doi:10.1515/9783110855449-039

Cited by 85 publications

(49 citation statements)

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“…The efficacy of EOs 14 and 15 may be imputable to the oxygenated monoterpenes, in particular to 4-terpineol, a-terpineol, cis-geraniol, b-citral, nerol and a-citral. Our results confirmed previous observations that this class of chemicals, especially phenolic substances, exhibits strong antimicrobial activity than hydrocarbon monoterpenes (Knobloch, Weigand, Weis, Schwarm, & Vigenschow, 1986;Sokovi c & van Griensven, 2006;Sokovi c, Tzakou, Pitarokili, & Couladis, 2002). Hydrocarbon monoterpenes are characterised by a low water solubility which limits their diffusion through the medium and their inactivity is closely related to their limited hydrogen bound capacity (Griffin, Markham, & Leach, 2000).…”

Section: Chemical Characterization Of Eossupporting

confidence: 91%

Inhibition of foodborne pathogen bacteria by essential oils extracted from citrus fruits cultivated in Sicily

et al. 2012

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Section: Chemical Characterization Of Eossupporting

confidence: 91%

Inhibition of foodborne pathogen bacteria by essential oils extracted from citrus fruits cultivated in Sicily

et al. 2012

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“…Essential oils are active against several microbial pathogens of man and animals and also against those of plants. This has been confirmed by a multitude of papers (Knobloch et al, 1986;Thompson, 1990;Sivropoulou et al, 1996;Sokovic´et al, 2002).…”

Section: Introductionmentioning

confidence: 60%

“…Also Oregano and Thyme oils were reported as highly effective against Phytophthora infestans causing late blight in tomato (Soylu et al 2006). A series of older publications reported analogous findings (Knobloch et al, 1986;Thompson, 1990;Sivropoulou et al, 1996, Sokovic´et al, 2002.…”

Section: Discussionmentioning

confidence: 90%

Antimicrobial activity of essential oils and their components against the three major pathogens of the cultivated button mushroom, Agaricus bisporus

2006

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Essential oils of Matricaria chamommilla, Mentha piperita, M. spicata, Lavandula angusti folia, Ocimum basilicum, Thymus vulgaris, Origanum vulgare, Salvia officinalis, Citrus limon and C. aurantium and their components; linalyl acetate, linalool, limonene, a-pinene, b-pinene, 1,8-cineole, camphor, carvacrol, thymol and menthol were assayed for inhibitory activity against the three major pathogens of the button mushroom, Agaricus bisporus, i.e. the fungi Verticillium fungicola and Trichoderma harzianum and the bacterium Pseudomonas tolaasii. The highest and broadest activity was shown by the Origanum vulgare oil. Carvacrol possessed the highest antifungal activity among the components tested.

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“…The importance of the presence of the hydroxyl group in phenolic compounds such as carvacrol and thymol was confirmed (Knobloch et al 1986;Dorman and Deans 2000;Ultee et al 2002). The activity of thymol (Fig.…”

Section: Lismentioning

confidence: 78%

Effect of oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) essential oils on Trypanosoma cruzi (Protozoa: Kinetoplastida) growth and ultrastructure

et al. 2006

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In the present work, we have investigated the effect of essential oils obtained from Origanum vulgare L. (oregano) and Thymus vulgaris L. (thyme) on growth and ultrastructure of diverse evolutive forms of Trypanosoma cruzi. Culture epimastigotes and bloodstream trypomastigotes were incubated for 24 h with different concentrations of oregano or thyme essential oils and with thymol (the main constituent of thyme), and the inhibitory concentration (IC)(50) was determined by cell counting. Crude extract of oregano essential oil inhibited epimastigote growth (IC(50)/24 h = 175 microg/ml) and also induced trypomastigote lysis (IC(50)/24 h = 115 microg/ml). Thyme essential oil presented IC(50)/24 h values of 77 microg/ml for epimastigotes and 38 mug/ml for trypomastigotes, while treatment with thymol resulted in an IC(50)/24 h of 62 microg/ml for epimastigotes and 53 microg/ml for trypomastigotes. Scanning electron microscopy of treated cells showed few morphological alterations at the plasma membrane. Observation by transmission electron microscopy showed cytoplasmic swelling with occasional morphological alterations in plasma and flagellar membrane. Our data indicate that oregano and thyme essential oils are effective against T. cruzi, with higher activity of thyme, and that thymol may be the main component responsible for the trypanocidal activity.

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Action of terpenoids on energy metabolism

Cited by 85 publications

References 0 publications

Inhibition of foodborne pathogen bacteria by essential oils extracted from citrus fruits cultivated in Sicily

Inhibition of foodborne pathogen bacteria by essential oils extracted from citrus fruits cultivated in Sicily

Antimicrobial activity of essential oils and their components against the three major pathogens of the cultivated button mushroom, Agaricus bisporus

Effect of oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) essential oils on Trypanosoma cruzi (Protozoa: Kinetoplastida) growth and ultrastructure

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