Abstract:Diethylstilbestrol (DS) has been shown to be active against staphylococci and other gram-positive bacteiia but not against gram-negative microorganisms. The present study extends these findings. Standardized suspensions of '4C-labeled Staphylococcus aureus serotypes III and IV and Shigella flexneri were prepared and exposed to pharmacological concentrations of DS (1 to 20 ,ung/ml) under diverse environmental conditions; the cells were removed by membrane filtration and the presence of radioactive substances in… Show more
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