Action observation facilitates motor cortical activity in patients with stroke and hemiplegia

Tani, Marina; Ono, Yumie; Matsubara, Masaharu; Ohmatsu, Satoko; Yukawa, Yoshihiro; Kohno, Masashi; Tominaga, Takanori

doi:10.1016/j.neures.2017.10.002

Cited by 62 publications

(65 citation statements)

References 41 publications

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“…Previous EEG and fMRI studies reported that AO induces bi-hemispheral activation in healthy participants and patients with stroke [18,45,49]. We observed that the difference in mu suppression between the affected and unaffected hemispheres was not significant, which is inconsistent with previous findings [7,17]. According to a study investigating the relationship between stroke lesion and mu suppression, the magnitude of mu suppression during AO was significantly reduced in the affected hemisphere when compared to the unaffected hemisphere, with greater damage in the inferior parietal lobule being associated with less mu suppression [17].…”

Section: Discussioncontrasting

confidence: 99%

“…This is consistent with other cortical activity studies during AO with EEG [7,39]. In a study by Tani et al, mu suppression during AO had a more widely distributed involvement of the prefrontal and parietal areas in addition to the sensorimotor cortex, compared to motor imagery in patients with stroke [7]. In a study by Kim and colleagues, a low level of alpha power in the frontal, central, parietal, and occipital areas during AO and a relatively lower level of alpha range compared to motor imagery were observed [39].…”

Section: Discussionsupporting

confidence: 93%

“…In this study, the BCI-AO game induced greater mu suppression in the parietal, temporal, occipital, and central motor areas than conventional AO. This is consistent with other cortical activity studies during AO with EEG [7,39]. In a study by Tani et al, mu suppression during AO had a more widely distributed involvement of the prefrontal and parietal areas in addition to the sensorimotor cortex, compared to motor imagery in patients with stroke [7].…”

Section: Discussionsupporting

confidence: 90%

“…Although AO has less mu suppression effect in the affected hemisphere [7,17], the BCI-AO game implemented in this study induced greater mu suppression both in the affected and unaffected hemispheres than conventional AO. Activation of the MNS in the affected hemisphere is important in the recovery of patients with stroke in the subacute phase [54].…”

Section: Discussionmentioning

confidence: 61%

“…Action observation (AO) is a promising technique used to enhance rehabilitation outcome by promoting motor cortical activation in patients with stroke [7]. Recent studies have reported the effectiveness of AO for motor performance improvement and motor memory formation in healthy people and patients with stroke [8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

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Brain Computer Interface-Based Action Observation Game Enhances Mu Suppression in Patients with Stroke

et al. 2019

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Action observation (AO), based on the mirror neuron theory, is a promising strategy to promote motor cortical activation in neurorehabilitation. Brain computer interface (BCI) can detect a user’s intention and provide them with brain state-dependent feedback to assist with patient rehabilitation. We investigated the effects of a combined BCI-AO game on power of mu band attenuation in stroke patients. Nineteen patients with subacute stroke were recruited. A BCI-AO game provided real-time feedback to participants regarding their attention to a flickering action video using steady-state visual-evoked potentials. All participants watched a video of repetitive grasping actions under two conditions: (1) BCI-AO game and (2) conventional AO, in random order. In the BCI-AO game, feedback on participants’ observation scores and observation time was provided. In conventional AO, a non-flickering video and no feedback were provided. The magnitude of mu suppression in the central motor, temporal, parietal, and occipital areas was significantly higher in the BCI-AO game than in the conventional AO. The magnitude of mu suppression was significantly higher in the BCI-AO game than in the conventional AO both in the affected and unaffected hemispheres. These results support the facilitatory effects of the BCI-AO game on mu suppression over conventional AO.

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