Action Mechanism of DLH-1777, a Novel 4-Pyridone-3-carboxamide Herbicide

The Porphyrin Pathway as a Herbicide Target Site

“…The DPE and certain other classes of herbicides cause rapid peroxidative bleaching and/or desiccation of plant tissues (3,(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42). The primary site of action of these herbicides is protoporphyrinogen oxidase (Protox) (37,(40)(41)(42), the last common enzyme in the synthesis of both heme and chlorophylls (Figure 1).…”

Efficacy of herbicides on weed suppression in transplanted finger millet (Eleusine coracana)

“…grasses, sedges and BLW, and the highest weed-control efficiency were recorded with pre-emergence application of oxyflourfen @ 0.1 kg a.i./ha, followed by azimsulfuron @ 20 g a.i./ha applied at 20 DAT, which was however, at par with pre-emergence application of oxyflourfen @ 0.1 kg a.i./ha, followed by hand-weeding at 20 DAT. This might be due to the effectiveness of pre-emergence application of oxyflourfen in controlling weeds through accumulation of protoporphyrin IX, a photosensitizing porphyrin, which destructs membrane and produces ethane resulting in killing of weeds at early stages (Morishima et al, 1990). Postemergence application of azimsulfuron at 20 DAT of finger millet was found to be superior in suppressing the annual sedges, viz.…”