Actinomycotic Fungal Infection of Foot – A Case Report.

Nayak, Ashok; Kulkarni, Sudheendra; Khodnapur, Gireesh; Santosh, Vinayak

doi:10.7439/ijbar.v4i12.590

Cited by 2 publications

(3 citation statements)

References 7 publications

(6 reference statements)

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“…Proximal tibiaAlcoholicssmokingActinomyces meyeriActinomycesSynovectomyPenicillin (IV) 8 W + penicillin (PO) 12 MCuredTekin et al [20]90/FKnee, ankle joint(proximal & distal tibia)UnknownUnknownActinomycesAmpicillin/sulbactam (IV) 2 W +Amoxicillin-clavulanate (PO) 6 MLower leg amputationKundu et al [6]50/MKnee joint(distal femur + proximal tibia)UnknownActinomycesActinomycesRepeated bone curettagePenicillin (IV) 6 WFailed- amputationNayak et.al. [17]30/MCalcaneusUnknownActinomycesMSSAActinomycesDebridement/Antibead insertionketaconazole + Tetracycline + Septran-DS (PO)6 WCuredYusof et al [7]34/MKnee joint, proximal tibiaUnknownNoneActinomycesBactrim and amoxycillin (PO) 6 MCured,But ROM limitationNandy et al [21]52/MTalus, medial malleolusNoneUnknownActinomycesClindamycin (IV) 3 WBelow knee amputationOur patient52/FDistal femurNoneNoneActinomycesRepeated bone curettagePenicillin (IV)8 W+ Amoxicillin-clavulanate (PO) 6 WCured…”

Section: Discussionmentioning

confidence: 99%

“…If there are atypical clinical findings or unexpected operative findings, we recommend culture, gram staining, Tb PCR, and pathologic examination. Early diagnosis and proper treatment for actinomycosis is important for a successful outcome and to prevent persistent draining sinus, deformation, sclerotic change of bone, and lower-limb amputation [6, 8, 17].…”

Section: Discussionmentioning

confidence: 99%

“…We did not use in our patient, Nayak et el. [17] reported that using bone cement (antibead) with a mixture of antibiotics can increase the local therapeutic effect. However, penicillin G is not stable at the heat which generated during the process of making antibiotic cements.…”

Section: Discussionmentioning

confidence: 99%

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Actinomycotic osteomyelitis of a long bone in an immunocompetent adult: a case report and literature review

Ryu

Jeon

Kwon

et al. 2019

BMC Musculoskelet Disord

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Background Actinomycosis is a rare, chronic granulomatous disease caused by Gram-positive anaerobic bacteria that colonize the oral cavity. Cervicofacial actinomycosis is the most frequent clinical presentation of actinomycosis, but hematogenous osteomyelitis at distant sites can occur in rare instance in immunocompromised or pediatric patients, only a few cases have been reported in healthy patients. Here we described a new case of distal femur osteomyelitis caused by Actinomyces in an adult patient who was immunocompetent and had no predisposing factors. Case presentation A woman aged 52 years with no history of trauma presented with severe pain, swelling, and increased local heat in the proximal area of the right knee 3 weeks after she first noticed discomfort. Magnetic resonance imaging showed persistent osteomyelitis of the distal metaphysis and diaphysis of the femur with a multifocal intraosseous abscess pocket. An incision and drainage of the abscess were conducted. The tissue culture, fungus culture, acid fast bacillus (AFB) culture, AFB smear, and tuberculosis polymerase chain reaction test results were negative. A pathologic examination confirmed the presence of actinomycosis. The patient was successfully treated with intravenous penicillin G for 8 weeks followed by oral amoxicillin-clavulanate for 6 weeks with repeated surgical debridement and drainage. After a 5-year follow up, the patient had no signs of recurring infection or complications and she had full range of movement in the affected knee. Conclusions Although rare, actinomycotic osteomyelitis can occur in healthy people. Furthermore, actinomycotic osteomyelitis is easily misdiagnosed as tuberculosis in areas with a high prevalence of tuberculosis. To detect and identify the bacteria accurately, pathologic examination should be performed as well as culture tests, because the probability for culture confirmation of actinomycosis is quite low. The initial treatment is vital to a successful outcome without ostectomy or amputation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Actinomycotic osteomyelitis of a long bone in an immunocompetent adult: a case report and literature review

Ryu

Jeon

Kwon

et al. 2019

BMC Musculoskelet Disord

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An Actinomyces Long-Bone Osteomyelitis Case Report and Review

Bush

Viggiano

Tayon

et al. 2021

Infect Dis Clin Pract

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Historically, anaerobic bacteria as monomicrobial pathogens or components of polymicrobial infections have been found to play a minor role in osteomyelitis. Various Actinomyces species reside as constituents of the normal human microbial flora found in the oropharynx and in the most people may also be present as commensal microorganisms in the gastrointestinal, genitourinary, and, to a lesser degree, the upper respiratory tracts. Bone infections due to Actinomyces species are relatively uncommon and usually associated with concomitant cervicofacial disease. To date, only a sparse amount of cases of long bone osteomyelitis due to Actinomyces bacteria have been published in the medical literature. We report a case of monomicrobial subacute late-onset tibia bone osteomyelitis involving Actinomyces presenting 10 years after an open reduction and internal fixation surgical procedure performed to stabilize a traumatic fracture and review actinomycotic osteomyelitis including the rare association of Actinomyces odontolyticus with long bone infections.

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Actinomycotic Fungal Infection of Foot – A Case Report.

Cited by 2 publications

References 7 publications

Actinomycotic osteomyelitis of a long bone in an immunocompetent adult: a case report and literature review

Actinomycotic osteomyelitis of a long bone in an immunocompetent adult: a case report and literature review

An Actinomyces Long-Bone Osteomyelitis Case Report and Review

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