Actinic granuloma. An annular connective tissue disorder affecting sun- and heat-damaged (elastotic) skin

O’Brien, John P.

doi:10.1001/archderm.111.4.460

Cited by 136 publications

(118 citation statements)

References 19 publications

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“…2 Hair and other skin appendages are preserved. The lesions are usually distributed on sun-exposed areas like the dorsum of the hands, forearms, neck, face, V of neck, and upper back (Figs.…”

Section: Clinical Presentationsmentioning

confidence: 99%

“…13 People with skin phototype I or II seem to be more affected than people with darker phototypes. 2 These lesions are usually asymptomatic, although some patients complain of mild pruritus or burning sensation. 13 It can last for months or years until spontaneous remission occurs.…”

Section: Clinical Presentationsmentioning

confidence: 99%

“…15 Ultraviolet (UV) radiation, especially UVA, because of its longer wavelength, and heat are recognized as causal factors, by changing the antigenicity of elastic fibers and producing an immune response. 2,16 However, collagen is not affected by actinic radiation. 17 Development of EAGCG has also been reported after prolonged UVA sun-bed exposure 16 and prolonged doxycycline phototoxicity, highlighting the importance of actinic radiation in the cause of this condition.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Elastolytic Actinic Giant Cell Granuloma

Gutiérrez‐González

Pereiro

Toribio

2015

Dermatologic Clinics

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Section: Clinical Presentationsmentioning

confidence: 99%

Section: Clinical Presentationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Elastolytic Actinic Giant Cell Granuloma

Gutiérrez‐González

Pereiro

Toribio

2015

Dermatologic Clinics

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“…1 Few cases have been reported in the literature and classification of this condition as a specific disease is questioned, since it is considered by some authors as a form of granuloma annulare that affects sun-exposed areas of the skin. 2 Clinically, it is characterized by erythematous papular lesions grouped together to form asymptomatic annular lesions with raised borders and atrophic centers.…”

Section: Introductionmentioning

confidence: 99%

Granuloma actínico de O'Brien: apresentação clínica exuberante

Lazzarini

Rotter

Farias

et al. 2011

An. Bras. Dermatol.

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O'Brien's actinic granuloma is a rare skin disease. Controversy continues over whether it should be considered a specific condition or a form of granuloma annulare located in sun-exposed areas. Its pathogenesis is unknown; however, the most widely accepted hypothesis suggests that solar radiation is the triggering factor. This paper describes the case of a 78-year old, fair-skinned male, who presented with a 10-year history of an infiltrate of annular erythematous papules on his forehead and left malar region. The diagnosis of O'Brien actinic granuloma was established from histopathology, since the clinical condition of the patient was extensive, unlike cases reported in the literature. Keywords: Giant cells; Granuloma; Granuloma, giant cell Resumo: O granuloma actínico de O'Brien é uma doença cutânea rara. Há muitas controvérsias na sua caracterização, podendo representar uma entidade nosológica distinta ou uma forma de granuloma anular em áreas expostas. A patogênese é desconhecida; no entanto, acredita-se que a radiação solar seja um fator desencadeante. Os autores relatam o caso de um paciente de 78 anos, branco, que apresentava há 10 anos pápulas eritematosas e infiltradas na fronte e hemiface à esquerda. O diagnóstico de granuloma actínico de O'Brien foi estabelecido a partir do exame histopatológico, uma vez que o quadro clínico exuberante apresentado pelo paciente diferia do de casos anteriormente observados.

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“…It was originally noted that these histopathologic changes were present in annular lesions in sun-damaged skin, and the term actinic granuloma (AG) was suggested for lesions with a distribution that correspond to sun-exposed skin and to indicate the pathogenic role of solar radiation [3]. However, investigators challenged the notion of AG as a distinct entity from GA, especially because of case reports of AG-like lesions in sun-protected areas.…”

mentioning

confidence: 99%

Photodistributed granuloma annulare

2017

Journal of the American Academy of Dermatology

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Actinic granuloma. An annular connective tissue disorder affecting sun- and heat-damaged (elastotic) skin

Cited by 136 publications

References 19 publications

Elastolytic Actinic Giant Cell Granuloma

Elastolytic Actinic Giant Cell Granuloma

Granuloma actínico de O'Brien: apresentação clínica exuberante

Photodistributed granuloma annulare

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