“…Upon mechanical stimulation of CMs, assembly may be controlled in an hour by an acute bout of activity through modification of the actin capping protein, CapZ, where load increases actin dynamics, filament assembly, and cell size (Lin et al, ). Mechanotransduction arising from stress or strain modifies the function of CapZ by phosphorylation via protein kinase C (PKC) (Disatnik, Buraggi, & Mochly‐Rosen, ; Kim, Cooper, & Sept, ; Wear & Cooper, ) , lipid binding with phosphatidylinositol 4,5‐bisphosphate (PIP2) (Hartman, Martin, Solaro, Samarel, & Russell, ; Li & Russell, ; Li, Tanhehco, & Russell, ), and through acetylation (Lin, Warren, Li, McKinsey, & Russell, ). Here, we concentrate on phosphorylation, which has recently been thoroughly reviewed (Scruggs, Wang, & Ping, ).…”