Actin and Actin‐Modulating Proteins

Staiger, Christopher J.; Hussey, Patrick J.

doi:10.1002/9781119312994.apr0092

Cited by 7 publications

(3 citation statements)

References 325 publications

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“…In species including Arabidopsis, Rice (Oryza sativa), and Cotton (Gossypium hirsutum), VLNs were also found to regulate the actin cytoskeletons by nucleating, severing, binding, capping, and depolymerizing [23,27,28]. There are five VLNs in both Arabidopsis and Rice, and fourteen in Cotton; these genes are widely expressed in a variety of tissues [27,[29][30][31], but only some of them have been functionally characterized. In Arabidopsis, loss−of−function of VLN1 and VLN4 caused longer and shorter root hairs, respectively, indicating they regulate the root hair growth in different ways [32]; VLN2 and VLN3 have been reported to regulate the normal development and organ morphogenesis of plants [33,34]; and VLN5 has an important role in the pollen tube growth [35].…”

Section: Introductionmentioning

confidence: 99%

Genome-Wide Identification and Expression Analysis of the VILLIN Gene Family in Soybean

Zhou

et al. 2023

Plants

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The VILLIN (VLN) protein is an important regulator of the actin cytoskeleton, which orchestrates many developmental processes and participates in various biotic and abiotic responses in plants. Although the VLN gene family and their potential functions have been analyzed in several plants, knowledge of VLN genes in soybeans and legumes remains rather limited. In this study, a total of 35 VLNs were characterized from soybean and five related legumes. Combining with the VLN sequences from other nine land plants, we categorized the VLN gene family into three groups according to phylogenetic relationships. Further detailed analysis of the soybean VLNs indicated that the ten GmVLNs were distributed on 10 of the 20 chromosomes, and their gene structures and protein motifs showed high group specificities. The expression pattern analysis suggested that most GmVLNs are widely expressed in various tissues, but three members have a very high level in seeds. Moreover, we observed that the cis−elements enriched in the promoters of GmVLNs are mainly related to abiotic stresses, hormone signals, and developmental processes. The largest number of cis−elements were associated with light responses, and two GmVLNs, GmVLN5a, and GmVLN5b were significantly increased under the long light condition. This study not only provides some basic information about the VLN gene family but also provides a good reference for further characterizing the diverse functions of VLN genes in soybeans.

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Section: Introductionmentioning

confidence: 99%

Genome-Wide Identification and Expression Analysis of the VILLIN Gene Family in Soybean

Zhou

et al. 2023

Plants

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“…Besides the Core, which is implicated in direct binding to F-actin, Arabidopsis fimbrins contain an N-ter and a C-terminal tail (called C-ter hereafter) (Fig. 5A) (48). We performed domain swapping experiments to determine the relative contribution of each domain to the distinct functions of FIM4 and FIM5 (Fig.…”

Section: Volume 291 • Number 34 • August 19 2016mentioning

confidence: 99%

The Structurally Plastic CH2 Domain Is Linked to Distinct Functions of Fimbrins/Plastins

Zhang

Chang

Zhang

et al. 2016

Journal of Biological Chemistry

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Fimbrins/plastins have been implicated in the generation of distinct actin structures, which are linked to different cellular processes. Historically, fimbrins/plastins were mainly considered as generating tight actin bundles. Here, we demonstrate that different members of the fimbrin/plastin family have diverged biochemically during evolution to generate either tight actin bundles or loose networks with distinct biochemical and biophysical properties. Using the phylogenetically and functionally distinct Arabidopsis fimbrins FIM4 and FIM5 we found that FIM4 generates both actin bundles and cross-linked actin filaments, whereas FIM5 only generates actin bundles. The distinct functions of FIM4 and FIM5 are clearly observed at singlefilament resolution. Domain swapping experiments showed that cooperation between the conformationally plastic calponinhomology domain 2 (CH2) and the N-terminal headpiece determines the function of the full-length protein. Our study suggests that the structural plasticity of fimbrins/plastins has biologically meaningful consequences, and provides novel insights into the structure-function relationship of fimbrins/plastins as well as shedding light on how cells generate distinct actin structures.

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“…There are five VLN genes in Arabidopsis , which is a model plant species. Although these genes are widely expressed in various plant tissues [ 26 , 27 , 28 , 29 ], only a subset of them has been functionally characterized. Specifically, the loss of AtVLN1 and AtVLN4 function has been associated with longer and shorter root hairs, respectively, indicating their distinct roles in the regulation of root-hair growth in Arabidopsis [ 30 ].…”

Section: Introductionmentioning

confidence: 99%

Genome-Wide Analysis of VILLIN Gene Family Associated with Stress Responses in Cotton (Gossypium spp.)

Deep,

Pandey

2024

CIMB

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The VILLIN (VLN) protein plays a crucial role in regulating the actin cytoskeleton, which is involved in numerous developmental processes, and is crucial for plant responses to both biotic and abiotic factors. Although various plants have been studied to understand the VLN gene family and its potential functions, there has been limited exploration of VLN genes in Gossypium and fiber crops. In the present study, we characterized 94 VLNs from Gossypium species and 101 VLNs from related higher plants such as Oryza sativa and Zea mays and some fungal, algal, and animal species. By combining these VLN sequences with other Gossypium spp., we classified the VLN gene family into three distinct groups, based on their phylogenetic relationships. A more in-depth examination of Gossypium hirsutum VLNs revealed that 14 GhVLNs were distributed across 12 of the 26 chromosomes. These genes exhibit specific structures and protein motifs corresponding to their respective groups. GhVLN promoters are enriched with cis-elements related to abiotic stress responses, hormonal signals, and developmental processes. Notably, a significant number of cis-elements were associated with the light responses. Additionally, our analysis of gene-expression patterns indicated that most GhVLNs were expressed in various tissues, with certain members exhibiting particularly high expression levels in sepals, stems, and tori, as well as in stress responses. The present study potentially provides fundamental insights into the VLN gene family and could serve as a valuable reference for further elucidating the diverse functions of VLN genes in cotton.

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Actin and Actin‐Modulating Proteins

Abstract: The sections in this article areIntroductionActinMyosinActin‐Binding Proteins: OverviewMonomer‐Binding ProteinsCross‐Linking and Bundling FactorsCapping FactorsNucleation ComplexesOtherF‐Actin Binding ProteinsConcluding RemarksAcknowledgements

Cited by 7 publications

References 325 publications

Genome-Wide Identification and Expression Analysis of the VILLIN Gene Family in Soybean

Genome-Wide Identification and Expression Analysis of the VILLIN Gene Family in Soybean

The Structurally Plastic CH2 Domain Is Linked to Distinct Functions of Fimbrins/Plastins

Genome-Wide Analysis of VILLIN Gene Family Associated with Stress Responses in Cotton (Gossypium spp.)

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