Actigraphic assessment of daily sleep–activity pattern abnormalities reflects self‐assessed depression and anxiety in outpatients with advanced non‐small cell lung cancer

Abstract

Lung cancer patients whose diurnal activity is disturbed by prolonged and frequent sedentary episodes and whose sleep is disturbed by frequent and prolonged waking are most anxious and depressed. These findings and relationships are masked by hospitalization. Since diurnal exercise improves both sleep and mood, it is reasonable to test whether enhancing daytime activity and nighttime sleep can diminish cancer-associated depression.

Amplitude of the rest–activity cycle in chronic obstructive pulmonary disease: an exploratory study

“…Increased comorbidity in our low-RA group is consistent with reduced amplitude of the circadian rest-activity cycle reported in other disease conditions, such as hypertension, 4 cancer, 1 and mood disorders, 46 all conditions taken into account by the COTE index. In their study of schizophrenia patients, Bromundt et al 19 found that low amplitude could be associated with disturbances of circadian rhythms, as shown by a delayed onset of melatonin secretion in relation to sleep time, and they proposed that circadian asynchrony may explain the strong association they found between low amplitude and low scores on many tests of cognitive functions.…”

Actigraphy for measurements of sleep in relation to oncological treatment of patients with cancer: A systematic review

“…Three studies [32,36,38] included controls; one with a properly matched control group [32]; one study used a historic control group [36]; and one study measured out-and inpatients; however, these were not measured during the same time period. Generally the oncological treatment studies were of low quality and of varying design (repeated-measure or cross sectional) (Table 3).…”

“…Data processing is an important part of getting correct sleep data, and only nine studies [27e30, 34,42,44,45,48] described some kind of data processing albeit heterogeneous in each study. Only two studies [28,38] mentioned which collection mode was chosen and all used zero crossing mode (ZCM). Likewise, few studies [28,51] described which algorithm was used for the sleep analysis, and in these cases it was the ColeeKripke algorithm.…”

“…Eight studies were performed in patients with breast cancer [27e34], one gynecological cancer [35], one colorectal cancer [36], one prostate cancer [37], one lung cancer [38], and one involving mixed cancer populations [39]. The 13 studies were conducted between 1999 and 2012.…”

“…In the study evaluating patients with advanced lung cancer [38] the study population was divided into out-patients and in-patients. The out-patient population was measured pre-chemotherapy, and the in-patient population was measured during first chemotherapy treatment.…”