Acrostart: Spanish retrospective study to determine the timeframe to achieve hormonal normalisation with initial Somatuline Autogel[reg] treatment in acromegaly patients in routine clinical practice
Abstract:Acromegaly is a rare, chronic endocrine disease, characterized by enhanced growth hormone (GH) secretion and elevated insulin-like growth factor-I (IGF-I) levels, the most frequent cause of which is a pituitary adenoma 1• Persistently elevated GH and IGF-I levels lead to substantial morbidity and mortality 2 • Control of GH and IGF-1 secretion is decisive in improving survival, 3 and optimum management of the disease requires a reduction in GH levels to <2.5 ng/mL and normalisation of IGF-1 levels 3• Somatosta… Show more
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