Acrolein Yields in Mainstream Smoke From Commercial Cigarette and Little Cigar Tobacco Products

Abstract

This article reports on the measured quantity of acrolein from 15 commercial sheet-wrapped cigars using a validated standard smoking test method that derivatizes acrolein in the mainstream smoke with DNPH solution, and uses Liquid Chromatography/Ultra-Violet Detection (LC/UV) for separation and detection. These acrolein yields were similar to the levels found in the smoke from 35 commercial cigarette products measured in the same manner. Although sheet-wrapped cigar data were slightly more variable than those found for the cigarette data, this article reports that the production of acrolein is similar to cigarettes. The results demonstrate that sheet-wrapped cigars can be tested for acrolein yields in mainstream smoke using the same methods used for the evaluation of cigarettes.

Electronic cigarette-generated aldehydes: The contribution of e-liquid components to their formation and the use of urinary aldehyde metabolites as biomarkers of exposure

“…Aldehydes are present in high concentrations in tobacco product-derived aerosols, including conventional cigarettes (700–800 µg/cigarette mainstream; 50–70 ppm per puff)(Dong and Moldoveanu 2004; Ghilarducci and Tjeerdema 1995), cigars (Cecil et al 2017), waterpipe (hookah)(Kassem et al 2014), heated cigarette (deBethizy et al 1990; Shihadeh et al 2012; Stanfill et al 2003; Stepanov et al 2008) and in electronic cigarettes (El-Hellani et al 2016; Goniewicz et al 2014; Kosmider et al 2014; McAuley et al 2012; Ogunwale et al 2017). The Institute of Medicine ranks aldehydes as the most significant cardiovascular toxins in tobacco smoke (Institute of Medicine 2010).…”

Little Cigars, Filtered Cigars, and their Carbonyl Delivery Relative to Cigarettes

“…This finding also agrees with previously literature for sheet-wrapped cigars, which found that the acrolein levels were similar between products. 21 …”

“…19 , 20 In one recent study, acrolein delivery in sheet-wrapped cigars was similar yet more variable than in cigarettes; however, no distinction was made between little cigars and filtered cigars. 21 To our knowledge there are no studies examining carbonyls in newer filtered cigars in comparison to either little cigars or cigarettes.…”

A Survey of Nicotine Yields in Small Cigar Smoke: Influence of Cigar Design and Smoking Regimens

“…24,26 Despite the physical and usage similarity between small cigars and cigarettes, only a few studies have examined small cigar products and smoke characteristics. [27][28][29][30][31][32][33] In a recent study, a large range (10.3-19.1 mg/g) was found in the nicotine content of small cigar tobacco, but, on average, concentrations (12.6 mg/g) were lower than those in cigarettes (19.2 mg/g). 31 Up-to-date data on nicotine yield in mainstream smoke collected under different standardized smoking regimens are available for commercial cigarettes [34][35][36] but not for cigars currently marketed in the United States.…”