Acroangiodermatitis (Pseudo-Kaposi sarcoma)

Abstract

Acroangiodermatitis or Pseudo-Kaposi sarcoma is a rare angioproliferative entity, related to chronic venous insufficiency or certain other vascular anomalies. It is often associated with chronic venous insufficiency, arteriovenous malformation of the legs, chronic renal failure treated with dialysis, paralyzed legs and amputation stumps. We hereby describe a case of 45 year old female presenting with pitting pedal edema, multiple ulcers over bilateral lower limbs with irregular margins with erythema and hyperpigmentation of the surrounding skin. Color Doppler study of bilateral lower limbs was normal. Histopathological examination from one of the lesions showed hyperplastic epidermis, proliferation of capillaries in dermis, hemosiderin deposits and lymphocytic infiltrate. These features thus confirmed the diagnosis of Acroangiodermatitis.

Pseudo-Kaposi’s Sarcoma: A Rare Case and Review

“…This sequence of events can trigger neovascularization and inflammatory cell infiltration, which can result in the proliferation of the disease. 12 …”

“…This sequence of events can trigger neovascularization and inflammatory cell infiltration, which can result in the proliferation of the disease. 12 The primary treatment for varicose veins involves using elastic bandages, while compression therapy is the primary treatment for venous insufficiency. 13 Other treatment options for pseudo-Kaposi's sarcoma include vein surgery, sclerotherapy, high ligation, valve grafting, and reconstruction.…”

Erythematous Plaque on the Lower Extremity of an Older Adult Man

“…It clinically presents as purplecolored, brown, or dusky patches, plaques, or nodules on the lower extremities, but the distribution of the lesions is diverse and depends on the underlying condition. 8 Histopathological examination shows a proliferation of newly formed thick-walled vessels lined by a single layer of endothelial cells. Extravasation of red blood cells, hemosiderin pigment deposition, and the presence of an inflammatory mononuclear infiltrate are common.…”

“…Acroangiodermatitis, or pseudo–Kaposi sarcoma, is a reactive process usually associated with venous insufficiency or other disorders giving impaired vascular flow. It clinically presents as purple-colored, brown, or dusky patches, plaques, or nodules on the lower extremities, but the distribution of the lesions is diverse and depends on the underlying condition . Histopathological examination shows a proliferation of newly formed thick-walled vessels lined by a single layer of endothelial cells.…”

Multiple acroangiodermatitis of the left big toe: A case report from the university clinic of dermatology-venereology of the national university hospital center Hubert Koutoukou MAGA of Cotonou in Benin

“…Chronic inflammation involving reactive proliferation of capillaries and dermal fibrosis due to chronic tissue hypoxia explains the occurrence of this condition, along with the notion of preceding trauma (pathergy phenomenon). This condition is rarely described, and it is important to be familiar with it to differentiate it from other commonly encountered vascular anomalies [4][5][6] . A thorough medical history allows for some diagnostic clues before confirmation with paraclinical tests such as Doppler ultrasound and, most importantly, histopathology.…”