Acremonium mycetoma in a heart transplant recipient

Geyer, A; Fox, Lindy P.; Husain, Sameera; Della‐Latta, Phyllis; Grossman, Marc E.

doi:10.1016/j.jaad.2006.08.001

Cited by 29 publications

(22 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The genus Acremonium currently contains approximately 100 species, and many are recognized as opportunistic pathogens of humans and animals, causing mycetoma, onychomycosis, and hyalohyphomycosis [19]–[21]. Clinical manifestations of hyalohyphomycosis that are caused by Acremonium include arthritis, osteomyelitis, peritonitis, endocarditis, pneumonia, cerebritis and subcutaneous infection [19].…”

Section: Discussionmentioning

confidence: 99%

Characterization of the Fungal Microbiota (Mycobiome) in Healthy and Dandruff-Afflicted Human Scalps

Park

et al. 2012

PLoS ONE

View full text Add to dashboard Cite

The human scalp harbors a vast community of microbial mutualists, the composition of which is difficult to elucidate as many of the microorganisms are not culturable using current culture techniques. Dandruff, a common scalp disorder, is known as a causative factor of a mild seborrheic dermatitis as well as pityriasis versicolor, seborrheic dermatitis, and atopic dermatitis. Lipophilic yeast Malassezia is widely accepted to play a role in dandruff, but relatively few comprehensive studies have been reported. In order to investigate fungal biota and genetic resources of dandruff, we amplified the 26S rRNA gene from samples of healthy scalps and dandruff-afflicted scalps. The sequences were analyzed by a high throughput method using a GS-FLX 454 pyrosequencer. Of the 74,811 total sequence reads, Basidiomycota (Filobasidium spp.) was the most common phylum associated with dandruff. In contrast, Ascomycota (Acremonium spp.) was common in the healthy scalps. Our results elucidate the distribution of fungal communities associated with dandruff and provide new avenues for the potential prevention and treatment of dandruff.

show abstract

Section: Discussionmentioning

confidence: 99%

Characterization of the Fungal Microbiota (Mycobiome) in Healthy and Dandruff-Afflicted Human Scalps

Park

et al. 2012

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Response to medical treatment is usually better in actinomycetoma than eumycetoma, which is difficult to treat with current therapies. [4]…”

Section: Introductionmentioning

confidence: 99%

Mycetoma in Iran: Causative agents and geographic distribution

Bassiri-Jahromi

2014

Indian J Dermatol

View full text Add to dashboard Cite

Background:Mycetoma is a chronic granulomatous disease caused by true fungi (eumycetoma) or filamentous bacteria (actinomycetoma). It usually involves the subcutaneous tissue after a traumatic inoculation of the causative organism. We reviewed retrospectively 13 patients with mycetoma.Materials and Methods:This study reports the etiologic agents and distribution of mycetoma in 35 cases from 1994 to2009 in Iran. The diagnostic of mycetoma were confirmed by histopathology and direct preparation, culture techniques, and histopathology of granules and surgical biopsies, radiological examination of the affected site.Results:Mycetoma was identified in 35 patients of 168 suspected patients (20.8%). They occurred in 22 male and 13 females. Their ages ranged from 14 to 80 years. The duration of the disease ranged from two months to 38 years. Sixteen patients had eumycetoma, and 19 patients had actinomycetoma, one of them had mix infections by eumycetoma and actinomycetoma. The majority of the patients were from central and states in south and north of Iran. The feet were most affected site (65.7%) of the cases, followed by hands (25.7%), face (2.8%), and trunk (2.8%), and buttock (2.8%). Most patients (68.5%) were more than 40 year-old. The male to female ratio was 5:3. The disease was abundant among housewife in urban and farmer in rural area of Iran. The most common prevalent mycetoma agents in this study were Actinomyces sp. There was a history of risk factors in 28.6% of patients in this study.Conclusion:Mycetoma occasionally occurs particularly in the South, Central, and North of Iran, and seen most often in persons, who live in hot, humid climates. If there are risk factors for invasive fungal infections traumatic inoculation with any fungus may result in rapid local spread and systemic disease, often with fatal outcome.

show abstract

“…Itraconazoie has been found to exhibit in vitro activity against Alternarla, but treatment failures with the compound have been reported (It). As more potent immunosuppressive drugs become available to prevent graft rejection, survival increases, expanding the population of immunocompromised patients and increasing the number of patients with opportunistic infections involving the skin (15). Voriconazole has been shown to be an efficient alternative to amphotericin B and surgical debridement for the treatment of cutaneous A. alternata infection in a liver transplant patient (14).…”

Section: Discussionmentioning

confidence: 99%