Acral lentiginous melanoma of the palm

Kato, Taizo; Ohkosi, K; Suetake, Takaki; Tabata, Noriko; Tagami, Hachiro

doi:10.1111/j.1365-2230.1996.tb00132.x

Cited by 4 publications

(4 citation statements)

References 3 publications

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“…1 Previous reports indicate that localization of melanoma on the palm is extremely rare. 2 Therefore, we report our experience with palmar melanoma in Korean patients through a retrospective analysis. Two hundred and sixty patients were diagnosed with primary cutaneous melanoma of the acral skin, including the feet, hands and nails, and were treated and followed up within our department between March 2005 and March 2016.…”

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confidence: 99%

“…The characteristics and treatment outcomes of palmar melanomas are not well described. 2 We raise the question as to whether the prognosis of acral melanoma is different between those on palms and soles. Melanoma on the foot predominates on the sole, whereas melanoma on the hand predominates on subungual areas.…”

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confidence: 99%

“…Only two previous studies evaluated pruritus in non-melanoma skin cancers. 1,2 Yosipovitch et al 1 reported that pruritus was prevalent in 46.6% of SCCs and 31.9% of BCCs, and Askari et al 2 reported that pruritus was prevalent in 27.3% of SCCs, 22.6% of BCCs and 25.5% of SKs. We thought that racial differences or a selection bias due to the small sample might have affected these differences in prevalence.…”

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confidence: 99%

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Scalp threading with polydioxanone monofilament threads: a novel, effective and safe modality for hair restoration

Bharti

Sonthalia²,

Patil³

et al. 2017

Acad Dermatol Venereol

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Follow-up visits were done at 2 weeks, 6 weeks and 12 weeks after the procedure.At 12 weeks, all patients (n = 5) had appreciable degree of increase in hair counts, confirmed with investigator-evaluated improvement in GPI (40%-75%; average of 57%) ( Fig. 2), trichoscopic hair count increment (48-93 HFU/cm 2 ; average of 67 HFU/cm 2 ) and patient satisfaction evaluated with VAS ranging from 4 to 8 with a mean of 6 ( Table 1).Except for mild pain experienced during thread insertion (n = 5), and mild transient swelling (n = 2), the procedure was very well tolerated by all. There was no case of significant bleeding, ecchymosis, persistent pain, headache or postprocedure infection.Polydioxanone (PDO) filament, a synthetic absorbable suture prepared from polyester, poly (p-dioxanone) has high flexibility and high retention strength, is non-allergenic and has a slow absorption rate (6-8 months). The risk of bacterial colonization or infection is minimal. As a non-surgical face lift modality, threads stimulate neocollagenesis within 2-3 weeks with clinical results expected to last for 2-3 years. 1 We preferred monofilament threads, instead of barbed/screwed.Although the exact mechanism of action of hair growth stimulation by PDO threads remains speculative, it is likely to be similar to that of microneedling, involving enhanced expression of hair-related genes, release of growth factors like PDGF and direct activation of stem cells in the hair bulge area. 3,5 A randomized trial by Dhurat et al. 4 had indeed displayed the superiority of the combination of microneedling with minoxidil over minoxidil alone in MPHL.Although this pilot study seems to offer scalp threading as a novel efficacious and safe non-surgical approach to hair regrowth, the limitations of this study including small number of cases, limited follow-up period and lack of scalp histological analysis warrant further research with controlled trials with a larger cohort. Further, the persistence of the hair growth-stimulating effect of the threads, and theoretical possibility of foreign body granuloma formation in the long term remain to be explored.Disclaimer "We confirm that the manuscript has been read and approved by all the authors, that the requirements for authorship as stated earlier in this document have been met, and that each author believes that the manuscript represents honest work".

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Scalp threading with polydioxanone monofilament threads: a novel, effective and safe modality for hair restoration

Bharti

Sonthalia²,

Patil³

et al. 2017

Acad Dermatol Venereol

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“…The first study of the geographical variation of rickets rates was published in 1890. 230 By 1921, research showed that sunlight and artificial UV could cure rickets 231 —and in 1922, vitamin D was identified as the active agent in preventing rickets. 232 …”

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confidence: 99%

The role of geographical ecological studies in identifying diseases linked to UVB exposure and/or vitamin D

Grant

2016

Dermato-Endocrinology

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Using a variety of approaches, researchers have studied the health effects of solar ultraviolet (UV) radiation exposure and vitamin D. This review compares the contributions from geographical ecological studies with those of observational studies and clinical trials. Health outcomes discussed were based on the author's knowledge and include anaphylaxis/food allergy, atopic dermatitis and eczema, attention deficit hyperactivity disorder, autism, back pain, cancer, dental caries, diabetes mellitus type 1, hypertension, inflammatory bowel disease, lupus, mononucleosis, multiple sclerosis, Parkinson disease, pneumonia, rheumatoid arthritis, and sepsis. Important interactions have taken place between study types; sometimes ecological studies were the first to report an inverse correlation between solar UVB doses and health outcomes such as for cancer, leading to both observational studies and clinical trials. In other cases, ecological studies added to the knowledge base. Many ecological studies include other important risk-modifying factors, thereby minimizing the chance of reporting the wrong link. Laboratory studies of mechanisms generally support the role of vitamin D in the outcomes discussed. Indications exist that for some outcomes, UVB effects may be independent of vitamin D. This paper discusses the concept of the ecological fallacy, noting that it applies to all epidemiological studies.

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Virale Erkrankungen: Klinik, Diagnostik und Therapie

Fölster‐Holst

2005

Fortschritte Der Praktischen Dermatologie Und Venerologie

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Acral lentiginous melanoma of the palm

Cited by 4 publications

References 3 publications

Scalp threading with polydioxanone monofilament threads: a novel, effective and safe modality for hair restoration

Scalp threading with polydioxanone monofilament threads: a novel, effective and safe modality for hair restoration

The role of geographical ecological studies in identifying diseases linked to UVB exposure and/or vitamin D

Virale Erkrankungen: Klinik, Diagnostik und Therapie

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