Acquisition and generalization of cough trigger beliefs in allergic rhinitis

Abstract

In allergic conditions, trigger identification is often inaccurate, and may be influenced by preexisting beliefs. In this study, we investigated the acquisition and generalization of symptom trigger beliefs in individuals with allergic rhinitis (n=24) and control participants (n=24). In a lab-based trigger acquisition task, unique exemplars of two trigger categories were either paired with saline inhalation (CS-category) or citric acid inhalation (CS+ category). The next day, we tested recognition and symptom expectancy for CS category exemplars and exemplars of novel trigger categories. Participants acquired differential symptom expectancies for CS+ compared to CS-exemplars, with faster acquisition in participants with rhinitis. Differential symptom expectancies persisted the next day, and generalized to novel trigger categories, with stronger generalization in rhinitis vs. control participants. These patterns of acquisition and generalization suggest that overgeneralization of trigger beliefs may complicate trigger identification in participants with allergic conditions.