Acquired vulval smooth muscle hamartoma in a postmenopausal woman, with no visible lesion

Toeima, Eman; Igali, Laszlo; Saleh, M

doi:10.3109/01443610903452781

Cited by 3 publications

(5 citation statements)

References 1 publication

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“…Although the etiopathogenesis of the SMH remains unclear, cases can be divided into two groups: congenital 1,5,9,10,16‐24 and acquired SMH 2‐4,6‐8,11,12,15,25‐32 . Eleven of our cases (41%) presented as a congenital lesion, most commonly located on the torso and lower extremity (six cases, 55%) followed by the upper extremity (two cases, 18%) and the head and neck area (two cases, 18%), and one case (9%) was located on the penile shaft.…”

Section: Discussionmentioning

confidence: 88%

“…Although the etiopathogenesis of the SMH remains unclear, cases can be divided into two groups: congenital 1,5,9,10,16-24 and acquired SMH. [2][3][4][6][7][8]11,12,15,[25][26][27][28][29][30][31][32] Eleven of our cases (41%) presented as a congenital lesion, most commonly located on the torso and lower extremity (six cases, 55%) followed by the upper extremity (two cases, 18%) and the head and neck area (two cases, 18%), and one case (9%) was located on the penile shaft. Similarly, acquired cases were also more commonly located on the torso and lower extremity (eight cases, 50%) followed by the head and neck region (three cases, 19%), the upper extremity (three cases, 19%) and the external genitalia (vulva and penile shaft) (two cases, 13%).…”

Section: Striated Muscle Hamartomamentioning

confidence: 99%

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Smooth muscle hamartoma and striated muscle hamartoma: Clinicopathologic characterization of two rare entities and literature review

González

Dehner

2020

J Cutan Pathol

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Smooth muscle hamartoma (SMH) and striated muscle hamartoma (STH) are anomalous proliferations of smooth muscle or striated muscle, respectively, in anatomic sites where these tissues are normally present. To date, only limited cases have been reported describing these lesions. In this study, we sought to characterize the clinicopathologic features of both SMH and STH. A total of 27 cases of SMH and 12 cases of STH from 1990 to 2020 were identified. SMH cases had a slight male predominance (63%) and a mean age of presentation of 20 years (range: 4 months‐91 years), with a mean size of 9.3 mm (±13.3). In contrast, STH were equally distributed in gender, with a mean age of presentation of 40 years (range: 3 months‐66 years) and a mean size of 5.7 mm (±3.6). SMH were more commonly located in the torso and extremities (70%) and STH in the head and neck area (92%). One case of SMH recurred after 1.1 years and in the initial diagnosis the lesion was present at the tissue edge. None of the cases of STH had a recurrence. We present the largest cohort of SMH and STH, and report the first case of a recurrent SMH, suggesting the importance of obtaining a clean margin for these lesions.

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Section: Discussionmentioning

confidence: 88%

Section: Striated Muscle Hamartomamentioning

confidence: 99%

Smooth muscle hamartoma and striated muscle hamartoma: Clinicopathologic characterization of two rare entities and literature review

González

Dehner

2020

J Cutan Pathol

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“…However, very heterogeneous morphologies have been described, ranging from nodular lesions to large neoformations, forming masses up to 30 cm in size 9,10 . The topographies reported are the scalp 10 , face 11 , neck 12,13 , trunk 9,14-18 , upper extremities 5,19,20 , lower extremities 3,21,22 , vulva 23,24 , and penoscrotal area 4,[25][26][27][28][29][30] . The present case is the second case of facial localization reported worldwide.…”

Section: Discussionmentioning

confidence: 99%

Acquired smooth muscle hamartoma with sebaceous component

Marín-Hernández¹,

Ramírez-Rico²

2022

BMHIM

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Background: Acquired smooth muscle hamartoma (ASMH) is a rare benign lesion characterized clinically by hyperpigmented plaques with hypertrichosis and some follicular papules. The main histologic finding is the presence of disorganized smooth muscle bundles in the dermis. Only 25 cases of ASMH have been reported in the literature. Clinical case: We present the case of an 18-year-old male who reported a pigmented area and increased hair growth on the left hemifacial with one year of evolution. Clinically, a plaque was observed in the preauricular region and on the left cheek with a linear Blaschkoid path, consisting of hyperpigmentation, hypertrichosis, and some papular lesions, with negative pseudo-Darier sign. Histological analysis showed an increase in the number of smooth muscle bundles in the middle and deep dermis surrounding abundant sebaceous glands and numerous hair follicles in different stages of evolution. Conclusions: The sebaceous component in this lesion was prominent. Therefore, we considered this lesion part of a spectrum where the acquired smooth muscle hamartoma and folliculosebaceous cystic hamartoma are found at the extremes. This case would fall in the middle of the range, as it combines both histological features.

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“…There are no published cases of congenital vulvar SMH. In addition, vulvar acquired SMH is very rare, with only 2 cases reported in the literature ( 4 , 5 ). The first patient had pruritic plaques and papules and was treated with antihistamines ( 4 ).…”

mentioning

confidence: 99%

“…The first patient had pruritic plaques and papules and was treated with antihistamines ( 4 ). The other patient had slight vulvar lichenification and experienced vulvar soreness, which was successfully treated with pain medication ( 5 ). There are no reports of a connection between herpes simplex viral infections and SMH in the literature.…”

mentioning

confidence: 99%