Acquired tracheomegaly in adults as a complication of diffuse pulmonary fibrosis

Woodring, John H.; Barrett, PA; Rehm,; Nurenberg, Pamela

doi:10.2214/ajr.152.4.743

Cited by 52 publications

(40 citation statements)

References 8 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The internal transverse diameter of the trachea is measured 2 cm above the top of the aortic arch on posterior anterior chest radiographs (10). Normally, the transverse diameter is13-25 mm in men and 10-21 mm in women (11).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Development of Tracheobronchomegaly during Mechanical Ventilation: An Unusual Case Report / Mekanik Ventilasyon Sırasında Gelişen Trakeobronkomegali: Ender Bir Olgu Sunumu

Çiçekci

2016

Anadolu Klin

View full text Add to dashboard Cite

Tracheobronchomegaly, first described in 1932 by Mounier-Kuhn, is a well-known clinical and radiological entity characterized by marked weakness of the trachea. It can be congenital or acquired. Some well-known inflammatory and infectious conditions have been associated with the acquired form. Endotracheal intubation can traumatize the trachea and usually results in focal stenosis, but may infrequently cause focal tracheobronchomegaly. It is not clearly understood why some cases result in stenosis and others in dilatation. This study reports the case of a patient whose clinical course was complicated by the development of intrathoracic focal tracheobronchomegaly during mechanical ventilation.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The weakness of the trachea is believed to result in inefficient cough. Diminished clearing of secretions leads to recurrent bronchopulmonary infections (2,10). A pulmonary function test reveals increased residual volume and obstruction (2,7).…”

Section: Discussionmentioning

confidence: 99%

Development of Tracheobronchomegaly during Mechanical Ventilation: An Unusual Case Report / Mekanik Ventilasyon Sırasında Gelişen Trakeobronkomegali: Ender Bir Olgu Sunumu

Çiçekci

2016

Anadolu Klin

View full text Add to dashboard Cite

show abstract

“…Our literature review also identified a cohort of 24 individuals who developed TBM after recurrent pulmonary infections (Type 2A) (e.g., Howland et al [18]) or Lung pulmonary fibrosis (Type 2B) (e.g., Woodring et al [19]). L'Allemand et al [20] described a subset of children with immune deficiency syndromes and frequent lung infections who developed TBM.…”

Section: Are There Distinct Clinical Sub-types Of Tbm?mentioning

confidence: 99%

“…The presence of more frequent cough was somewhat associated with the presence of TBM (which was noted in 10 of 34 patients) [19]. Woodring et al [4] hypothesized that increased elastic recoil pressure in lungs with advanced fibrosis exerts traction on the trachea, resulting in tracheomegaly, perhaps with added damage to the tracheal wall from chronic infection.…”

Section: Are There Distinct Clinical Sub-types Of Tbm?mentioning

confidence: 99%

A Clinical Classification Scheme for Tracheobronchomegaly (Mounier-Kuhn Syndrome)

Payandeh

McGillivray

McCauley

et al. 2015

Lung

View full text Add to dashboard Cite

show abstract

“…The diagnosis is based on abnormally increased anteroposterior and/or transverse diameters of the trachea. TBM is considered to be a congenital disorder, but several reports suggest that TBM could be an acquired condition especially when associated with inflammatory processes affecting the trachea or bronchi, such as cystic fibrosis (CF) [7] or lung fibrosis [8]. …”

Section: Introductionmentioning

confidence: 99%

Respiratory Conditions Associated with Tracheobronchomegaly (Mounier-Kuhn Syndrome): A Study of Seventeen Cases

Schmitt

Dalar²,

Jouneau

et al. 2016

Respiration

View full text Add to dashboard Cite

Background: Mounier-Kuhn syndrome (MKS) is a rare disorder characterized by enlargement of the trachea and main bronchi and associated with recurrent respiratory tract infections. Objective: This multicenter, retrospective study was carried out to describe respiratory conditions associated with tracheobronchomegaly. Methods: Nine institutions involved in the ‘Groupe d'Endoscopie de Langue Française' (GELF) participated in this study. A standard form was used to record patient characteristics, treatments and follow-up from medical charts. Results: Seventeen patients, 53% male, aged 58 ± 18 years at diagnosis were included. Recurrent infections revealed MKS in 88% of cases. Main comorbid conditions were diffuse bronchiectasis in 88% of patients and tracheobronchomalacia in 67% of cases. The exacerbation rate was 1.5 exacerbations/patient/year. The main non-respiratory morbid condition was gastroesophageal reflux disease in 29% of cases. Interventional bronchoscopy was performed in seven patients (41%), consisting of laser (n = 2) and tracheal stenting (n = 5). Complications related to stents were observed in 80% of cases with a mean stent duration of 8 months. Four deaths, including three due to respiratory causes, occurred during follow-up. Conclusions: This is the largest series of MKS reported in the literature, showing that bronchiectasis and tracheobronchomalacia are the main associated morbid conditions that constitute a challenge for treatment.

show abstract

Acquired tracheomegaly in adults as a complication of diffuse pulmonary fibrosis

Cited by 52 publications

References 8 publications

Development of Tracheobronchomegaly during Mechanical Ventilation: An Unusual Case Report / Mekanik Ventilasyon Sırasında Gelişen Trakeobronkomegali: Ender Bir Olgu Sunumu

Development of Tracheobronchomegaly during Mechanical Ventilation: An Unusual Case Report / Mekanik Ventilasyon Sırasında Gelişen Trakeobronkomegali: Ender Bir Olgu Sunumu

A Clinical Classification Scheme for Tracheobronchomegaly (Mounier-Kuhn Syndrome)

Respiratory Conditions Associated with Tracheobronchomegaly (Mounier-Kuhn Syndrome): A Study of Seventeen Cases

Contact Info

Product

Resources

About