Acquired Toxoplasmic Infection as the Cause of Toxoplasmic Retinochoroiditis in Families

Incidence of acute symptomatic toxoplasma retinochoroiditis in south London according to country of birth

“…Retinochoroiditis due to acquired toxoplasma infection has been well documented4 6 17 and, in the absence of clinical or serological indicators of recent infection, is indistinguishable from congenital infection. Outbreaks of toxoplasma retinochoroiditis have been reported in siblings,29 30 and in a population based study in southern Brazil, where toxoplasmosis is common, a fifth of adults had toxoplasma retinochoroidal lesions 31. Most toxoplasma retinochoroiditis was due to acquired infection as only 1% of cord blood samples in that population were positive for IgM.…”

Toxoplasma gondii in the peripheral blood of patients with acute and chronic toxoplasmosis

“…All samples were blindly analysed; the clinical status and diagnosis of each patient were revealed only after laboratory analysis was finished. Diagnosis was established according to the criteria published elsewhere 6. All patients were negative for syphilis (VDRL), tuberculosis (PPD) and HIV infection (ELISA).…”

Epidemiology of Ocular Toxoplasmosis

“…60,61 It has been estimated that infection with T. gondii is responsible for up to 30% of infectious uveitis in Brazil. 10,62,63 Even within Brazil the prevalence of chorioretinitis in adults may vary from 2% in northern Brazil 64 to 25% in southern Brazil. 65 A study from Columbia found that 6% of healthy adults had retinal scars and T. gondii-specific IgG antibodies.…”