2018
DOI: 10.3205/oc000088
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Acquired perforating collagenosis associated with ranibizumab injection and succesfully switched to aflibercept

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“…ARPC usually affects patients with a variety of systemic disorders, and diabetes mellitus and chronic renal failure are the most common. In addition, malignancies, collagen vascular diseases (lupus, dermatomyositis), viral infection, lung fibrosis, thyroid dysfunction and drug induction have been reported ( 1 , 3 ). The disease classically erupts as multiple, pruritic umbilicated papules with a central keratotic plug, with common sites including the trunk and extremities ( 1 , 4 ).…”
Section: Discussionmentioning
confidence: 99%
“…ARPC usually affects patients with a variety of systemic disorders, and diabetes mellitus and chronic renal failure are the most common. In addition, malignancies, collagen vascular diseases (lupus, dermatomyositis), viral infection, lung fibrosis, thyroid dysfunction and drug induction have been reported ( 1 , 3 ). The disease classically erupts as multiple, pruritic umbilicated papules with a central keratotic plug, with common sites including the trunk and extremities ( 1 , 4 ).…”
Section: Discussionmentioning
confidence: 99%