Acquired Nystagmus in Early Childhood

Presentation of TRPM1-Associated Congenital Stationary Night Blindness in Children

“…14,15 For early-onset nystagmus without apparent ocular cause, neuroimaging is often completed. [16][17][18][19] Unnecessary testing can be avoided by a careful history combined with salient clinical features, ffERG, and molecular confirmation.…”

Atypical spasmus nutans as an initial sign of thalamic neoplasm

“…Classically, the condition is transient and not associated with any discernible underlying pathology [4]. Atypical spasmus nutans is often diagnosed when some of the features of the classic syndrome are absent or when the patient's age at presentation is inappropriate [9]. The ophthalmotogic literature recognizes dissociated nystagmus alone or in combination with head tilt as atypical spasmus nutans [4,7].…”

“…The ophthalmotogic literature recognizes dissociated nystagmus alone or in combination with head tilt as atypical spasmus nutans [4,7]. In the absence of the classic triad of symptoms, atypical spasmus nutans has been reported frequently in association with anatomic lesions, specifically tumors involving the optic chiasm and hypothalamus [7][8][9]11]. Some authorities suggest applying the term pseudo° spasmus nutans to the entity of atypical spasms nutans with a well-defined underlying pathologic process [D. G. Cogan, personal communication, 1986].…”

“…There may be associated head tilt or head nodding, but the sequence of appearance or the age at presentation may be atypical. Several authors have reported the association of atypical spasmus nutans with lesions of the anterior optic pathway [7][8][9] or with the anterior third ventricular region [7,9].…”

Torticollis, head bobbing and oscillatory eye movements in a 14 year old child

“…However, various intracranial lesions may be manifested in some cases, such as cerebellar hypoplasia, third ventricular tumor, retinal dystrophy, and achromatopsia. [56] In about 2% cases, structural lesions affecting the anterior visual pathway, like, optic nerve glioma, optic atrophy, and relative afferent pupillary defect are the additional findings. [7]…”