Acquired ichthyosis and secondary hyperparathyroidism with systemic lupus erythematosus

Peng, Tao; Hu, Zhao; Gao, Zhi-Gang; Cai, Duan; Yang, Xiao

doi:10.1177/0961203314554250

Cited by 5 publications

(5 citation statements)

References 5 publications

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“…In some patients with chronic kidney disease, PTH increased due to compensation, and in some patients with AKI, increased levels of PTH was also seen. [ 16 ] In the present case report, the PTH and Scr levels were significantly increased at admission, but scintigraphy of the parathyroid appeared normal and there was no adenoma or hyperplasia. The PTH level decreased to normal after therapy, and the event was considered secondary hyperparathyroidism.…”

Section: Discussionmentioning

confidence: 43%

Nitrite-induced acute kidney injury with secondary hyperparathyroidism

Peng

Yang

et al. 2018

Medicine

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Rationale:Acute kidney injury (AKI) with hyperparathyroidism caused by nitrite was rare, and renal function and parathyroid hormone (PTH) decreased to normal range after therapy.Patient concerns:Acute kidney injury was diagnosed in a 40-year-old male with hyperparathyroidism and cyanosis of his hands and both forearms.Diagnoses:The patient ate some recently pickled vegetables, and he experienced nausea, vomiting and diarrhoea without oliguria or anuria; Additionally, his hands and both forearms had a typical blue ash appearance. After admission, the laboratory findings indicated theincreasing serum creatinine (Scr) and parathyroid hormone (PTH). He was diagnosed as acute kidney injury with hyperparathyroidism caused by nitrite.Interventions:The patient stopped eating the pickled vegetables and was given rehydration, added calories and other supportive therapy without any glucocorticoids.Outcomes:According to his clinical manifestations, laboratory findings and imaging results, the patient was diagnosed with acute kidney injury with secondary hyperparathyroidism. He was given symptomatic supportive care therapy. After one week, the serum creatinine, parathyroid hormone (PTH), hypercalcemia, hyperphosphatemia, proteinuria, and urine red blood cell values decreased to normal range.Lessons:Nitrite-induced acute kidney injury with secondary hyperparathyroidism was relatively rare. After therapy, the function of the kidney and parathyroid returned to normal. This case suggests that detailed collection of medical history, physical examination and correct symptomatic treatment is very important.

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Section: Discussionmentioning

confidence: 43%

Nitrite-induced acute kidney injury with secondary hyperparathyroidism

Peng

Yang

et al. 2018

Medicine

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“…Ichthyosiform skin lesions appeared and regressed during states of elevated and normalized parathyroid hormone levels, respectively. Finally, a 14‐year‐old girl with SLE, secondary hyperparathyroidism and AI showed clinical improvement of all three conditions while taking a methylprednisolone regimen; however, a pathomechanism for AI in this case remained unclear 52 …”

Section: Metabolic Disordersmentioning

confidence: 82%

“…Finally, a 14-year-old girl with SLE, secondary hyperparathyroidism and AI showed clinical improvement of all three conditions while taking a methylprednisolone regimen; however, a pathomechanism for AI in this case remained unclear. 52 A few cases of AI in the setting of various other metabolic disorders have been presented, including porphyria cutanea tarda, familial combined factor V and factor VIII deficiency, hypopituitarism and chronic hepatic disease (Table 1). 2,67,68…”

Section: Eta Bol Ic Disor De R Smentioning

confidence: 99%

“…Accordingly, one hypothesis proposed that AI is caused by disrupted epidermal lipid metabolism secondary to suppressed HMG-CoA reductase activity in hypothyroid states. 50 Other autoimmune and chronic inflammatory conditions have been rarely associated with AI, including inflammatory bowel disease, systemic lupus erythematosus (SLE), graft-versus-host disease, eosinophilic fasciitis and systemic sarcoidosis 48,[50][51][52][53][54][55][56][57] (Figure 1d).…”

Section: Au Toi M Mu N E a N D Chron Ic I N Fl A M M Atory Con Ditionsmentioning

confidence: 99%

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Acquired ichthyosis, asteatotic dermatitis or xerosis? An update on pathoetiology and drug‐induced associations

Park

Saeidian

Youssefian

et al. 2022

Acad Dermatol Venereol

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Acquired ichthyosis (AI) or conditions mimicking ichthyosis have been documented for well over a century. AI is limited to the skin, but can be the first presenting sign of an underlying disease or an adverse effect of select medications or environmental exposures. 1,2 Most heritable ichthyoses, with the exceptions of late-onset ichthyosis vulgaris (IV) and Refsum disease, typically manifest between the immediate postnatal period and 5 years of age. 2 AI, however, does not follow an obvious age distribution; rather, the appearance and disappearance of AI tend to coincide with onset and resolution of an inciting factor. Clinically, AI closely resembles IV with diffuse, symmetrically distributed, white-to-brown scales which can be confused with severe cases of xerosis or eczema (Figure 1a-c). 1 Histopathology of AI usually shows varying degrees of orthohyperkeratosis, a uniformly diminished or absent granular layer, and lack of dermal inflammation. 1,3 In patients with suspected AI, a detailed investigation into the clinical course typically does not yield personal or family history of ichthyosis, atopy, keratosis pilaris or other keratodermaassociated phenotypes seen with the heritable ichthyoses. 1,2 In this article, we provide an up-to-date overview of AI and the pathomechanisms suggested in the literature. While the associated clinical features in many cases of AI are unknown, detailed examples are provided for the medical conditions, medications and exposures with clinical importance. In

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“…В работах отечественных и зарубежных авторов приводятся многочисленные причины приобретенного ихтиоза: чрезмерный уход за кожей (встречается в основном у лиц зрелого возраста); злокачественные опухоли [29-32]; почечная недостаточность; аутоиммунные заболевания; инфекционные заболевания (как правило, ВИЧ инфекция и туберкулез); употребление определенных препаратов (гиполипидемические, психотропные, циметидин, клофазимин) [33]; недостаточно сбалансированное питание (недостаточность витамина А, кахексия) [34]; расстройства гормонального характера (гипотиреоз, гиперпаратиреоз, пангипопитуитаризм) [35,36]; хронические воспалительные заболевания кишечника (неспецифический язвенный колит, болезнь Крона). Патогенез приобретенного ихтиоза до настоящего времени недостаточно изучен.…”

Section: разделunclassified

Ichthyosis (concept, pathohistology, clinical picture, treatment)

Takhtarova

Геннадьевна²,

Хисматуллина

et al. 2021

Vestnik dermatologii i venerologii

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Ichthyosis is a skin disease that is hereditary, has pronounced symptoms in the form of a violation of the skin, and the presence of formations resembling fish scales. It is possible to distinguish different approaches to the definition of ichthyosis, based on the modern study of this issue. Ichthyosis is classified by type: congenital and acquired. Congenital ichthyosis has its own classification depending on the manifestation of changes in the skin, the course of the disease, concomitant pathologies. Congenital ichthyosis is divided into ordinary (vulgar autosomal dominant, simple) ichthyosis, lamellar ichthyosis (dry ichthyosiform erythroderma, "collodion child", lamellar ichthyosis), X-linked ichthyosis (ichthyosis associated with the X chromosome, blackening ichthyosis), congenital bullous ichthyosiform erythroderma (erythroderma Broca's disease, ichthyosiform epidermolytic hyperkeratosis), fetal ichthyosis (intrauterine ichthyosis, universal hyperkeratosis, "Harlequin fetus", congenital keratosis), other congenital ichthyosis. Ichthyosiform conditions (the so-called acquired ichthyosis) are divided into symptomatic, age-related (senile), discoid ichthyosis. The causes of acquired ichthyosis can be various diseases, taking medications, improper skin care, unbalanced nutrition. Each form of ichthyosis differs by the type of inheritance, prevalence in the population, clinical picture, verified by histological examination of skin biopsies and electron microscopic examination of the skin. It may be accompanied by seasonality of exacerbation of the clinical picture, association with other diseases (allergic, diseases of the gastrointestinal tract, congenital malformations). There is no specific treatment for ichthyosis. In systemic therapy, derivatives of vitamin A are used, keratolytics, as well as moisturizing and emollient agents are used for external treatment. The use of therapeutic baths, general ultraviolet irradiation is effective.

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Acquired ichthyosis and secondary hyperparathyroidism with systemic lupus erythematosus

Cited by 5 publications

References 5 publications

Nitrite-induced acute kidney injury with secondary hyperparathyroidism

Nitrite-induced acute kidney injury with secondary hyperparathyroidism

Acquired ichthyosis, asteatotic dermatitis or xerosis? An update on pathoetiology and drug‐induced associations

Ichthyosis (concept, pathohistology, clinical picture, treatment)

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