Acquired ichthyosis and pityriasis rotunda

Pityriasis rotunda: a case from Turkey

“…The diagnosis of pityriasis rotunda is made by both clinical and histopathological findings. Histopathology of lesional skin can reveal variable changes including hyperkeratosis with follicular plugs seen within hair follicles, a thin or absent granular layer, slight spongiosis, pigmented basal layer, pigmentary incontinence, and perivascular infiltrate . These findings were consistent with our case's histopathology.…”

“…The etiology of pityriasis rotunda remains unknown. Most authors believe that it is a form of acquired ichthyosis, a delayed presentation of congenital ichthyosis, or a cutaneous manifestation of systemic disease . It may be associated with a variety of conditions, including tuberculosis, malnutrition, and malignancy, but many cases occur in the absence of underlying disease as in our patient .…”

Paraneoplastic Syndromes

“…The condition in most patients follows the diagnosis of the cancer and usually is observed in the late stages of the disease. 56 Treatment is pa r a n e o p l a s t i c s y n d ro m e s 1 5 1 1 …”

Skin diseases described in Japan 2004

“…The histopathologic features of pityriasis rotunda are essentially the same as those in ichthyosis vulgaris, and consist of mild hyperkeratosis with a thinned granular layer. Since the histopathology of this condition is identical with that of ichthyosis vulgaris, some authors consider pityriasis rotunda as a special form of “acquired ichthyosis vulgaris” [15]. The differential diagnosis includes pityriasis versicolor, erythrasma, and parapsoriasis en plaques.…”