Acoustic Streaming and Microparticle Enrichment within a Microliter Droplet Using a Lamb-Wave Resonator Array

Zhang, Hongxiang; Tang, Zifan; Wang, Zhan; Pan, Shuting; Han, Ziyu; Sun, Chongling; Zhang, Menglun; Duan, Xuexin

doi:10.1103/physrevapplied.9.064011

Cited by 23 publications

(20 citation statements)

References 36 publications

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“…The above term can derive the equation of body force. Using the first and second order quantities of complex exponential series solution to obtain steady state solution of eqs and , and the body force can be expressed by eq : ν 1 is first order solution of velocity and ν 1 * is conjugation of ν 1 . ν 1 represents vibration of fluid (SI Figure S9), and it exists in the region with acoustic pressure (Figure ), that is, the area from the SMR surface to 10s of micrometers right above it.…”

Section: Resultsmentioning

confidence: 99%

Miniature Gigahertz Acoustic Resonator and On-Chip Electrochemical Sensor: An Emerging Combination for Electroanalytical Microsystems

et al. 2019

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Performance of electroanalytical lab-on-a-chip devices is often limited by the mass transfer of electroactive species toward the electrode surface, due to the difficulty in applying external convection. This article describes the powerful signal enhancement attained with a 2.54 GHz miniature acoustic resonator integrated with an electrochemical device in a miniaturized cell. Acoustic resonator and an on-chip gold thin-film three-electrode electrochemical cell were arranged facing each other inside a structured poly(methyl methacrylate) chamber. Cyclic voltammetric and chronoamperometric responses of 1 mM ferrocene-methanol were recorded under resonator's actuation at powers ranging from 0 to 1 W. Finite element analysis was carried out to study the sono-electroanalytical process. Acoustic resonator's actuation greatly enhances the mass transport of electroactive species toward the electrode surface. The diffusion limited cyclic voltammetric and chronoamperometric currents increase around 10 and 20 times, respectively, with an input power of 1 W compared to those recorded under stagnant conditions. The improvement in electroanalytical process is mainly associated with acoustic resonator's vibration induced fluid streaming. The advantages of a miniaturized acoustic resonator, including the submillimeter small size, amenability for mass fabrication, cost effectiveness, low energy consumption, as well as outstanding enhancement of coupled electrochemical processes, will enable the production of highly sensitive compact electroanalytical devices.

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Section: Resultsmentioning

confidence: 99%

Miniature Gigahertz Acoustic Resonator and On-Chip Electrochemical Sensor: An Emerging Combination for Electroanalytical Microsystems

et al. 2019

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“…SAWs, as well as thickness‐mode bulk waves, can also be generated on thin piezoelectric films (the latter being known as thin film bulk acoustic resonators, and has the advantage of overcoming challenges associated with fabricating interdigitated transducers with micron or submicron widths and thicknesses necessary to generate SAWs at higher (e.g., GHz) frequencies), on which similar azimuthal microfluidic centrifugation flows can be effected. In addition to demonstrating the microvortical flow arising from these devices for various applications, including hydrodynamic particle trapping, biomolecular concentration and the shearing of polyelectrolyte films for drug release, the piezoelectric films can be overlaid onto regular substrates so as to circumvent the need for the piezoelectric substrate as well as to facilitate microfluidic operations on flexible substrates .…”

Section: Active Actuationmentioning

confidence: 99%

On‐Chip Generation of Vortical Flows for Microfluidic Centrifugation

Ahmed

Ramesan

Lee

et al. 2019

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Microcentrifugation constitutes an important part of the microfluidic toolkit in a similar way that centrifugation is crucial to many macroscopic procedures, given that micromixing, sample preconcentration, particle separation, component fractionation, and cell agglomeration are essential operations in small scale processes. Yet, the dominance of capillary and viscous effects, which typically tend to retard flow, over inertial and gravitational forces, which are often useful for actuating flows and hence centrifugation, at microscopic scales makes it difficult to generate rotational flows at these dimensions, let alone with sufficient vorticity to support efficient mixing, separation, concentration, or aggregation. Herein, the various technologies—both passive and active—that have been developed to date for vortex generation in microfluidic devices are reviewed. Various advantages or limitations associated with each are outlined, in addition to highlighting the challenges that need to be overcome for their incorporation into integrated microfluidic devices.

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“…Here, numerical simulations may play a crucial role, both in improving the understanding of the underlying physical acoustofluidic processes, and in easing the cumbersome development cycle consisting of an iterative series of creating, fabricating, and testing device designs. An increasing amount of numerical studies include piezoelectric dynamics in two-dimensional (2D) models [25][26][27][28], but in most cases the piezoelectric transducers are introduced in numeric models in the form of 2331-7019/19/12(4)/044028 (17) 044028-1 © 2019 American Physical Society analytic approximations [29][30][31][32][33][34], and designs are often based on a priori knowledge of the piezoelectric effect in the unloaded substrates typically applied in telecommunications. In acoustofluidic devices, the acoustic impedance of the contacting fluid is much closer to that of the substrate, causing waves to behave very differently from those in telecommunications devices.…”

Section: Introductionmentioning

confidence: 99%

Three-Dimensional Numerical Modeling of Surface-Acoustic-Wave Devices: Acoustophoresis of Micro- and Nanoparticles Including Streaming

et al. 2019

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Surface-acoustic-wave (SAW) devices form an important class of acoustofluidic devices, in which acoustic waves are generated and propagate along the surface of a piezoelectric substrate. Despite their widespread use, only a few fully three-dimensional (3D) numerical simulations have been reported in the literature. In this paper, we present a 3D numerical simulation taking into account the electromechanical fields of the piezoelectric SAW device, the acoustic displacement field in the attached elastic material, in which a liquid-filled microchannel is embedded, the acoustic fields inside the microchannel, and the resulting acoustic radiation force and streaming-induced drag force acting on micro-and nanoparticles suspended in the microchannel. A specific device design is presented, for which numerical predictions of the acoustic resonances and the acoustophoretic response of suspended microparticles in three dimensions are successfully compared with experimental observations. The simulations provide a physical explanation of the observed qualitative difference between devices with acoustically soft and hard lids in terms of traveling and standing waves, respectively. The simulations also correctly predict the existence and position of the observed in-plane streaming-flow rolls. The simulation model presented may be useful in the development of SAW devices optimized for various acoustofluidic tasks.

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Acoustic Streaming and Microparticle Enrichment within a Microliter Droplet Using a Lamb-Wave Resonator Array

Cited by 23 publications

References 36 publications

Miniature Gigahertz Acoustic Resonator and On-Chip Electrochemical Sensor: An Emerging Combination for Electroanalytical Microsystems

Miniature Gigahertz Acoustic Resonator and On-Chip Electrochemical Sensor: An Emerging Combination for Electroanalytical Microsystems

On‐Chip Generation of Vortical Flows for Microfluidic Centrifugation

Three-Dimensional Numerical Modeling of Surface-Acoustic-Wave Devices: Acoustophoresis of Micro- and Nanoparticles Including Streaming

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