Acoustic Radiation Pressure in a Traveling Plane Wave

In this investigation, acoustic radiation force was used as a stimulus to determine the threshold for tactile perception in the human finger and upper forearm as a function of frequency and pulse duration. Initially, a small (1.8-cm2) acoustically reflecting disk was affixed to the anatomical exposure site to maximize the delivered radiation force. Exposures were performed using a 2.2-MHz unfocused source modulated to produce square waves at 50, 100, 200, 500, and 1000 Hz. For the finger, maximum tactile sensitivity occurred at 200 Hz with a threshold radiation force of approximately 0.4 mN. For single pulses of 1 to 100 ms at 2.2 MHz, the threshold forces were an order of magnitude greater than for continuous exposure modulated at 200 Hz. Thresholds for pulse durations of 0.1 ms were somewhat greater than for pulses longer than 1 ms. Subsequently, thresholds of tactile perception were determined for direct exposure of the upper forearm (avoiding bone) to single pulses of 2.2-MHz ultrasound. Comparison of perception thresholds with and without a reflecting material over the tissue were consistent with the hypothesis that the tactile sensation experienced when tissue is exposed to ultrasound is its response to the radiation force associated with the transfer of momentum from the sound field to the tissue medium.

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“…For a plane wave incident normally on a perfectly absorbing target the Langevin radiation force is (Rooney and Nyborg, 1972) …”

Section: Computation Of Radiation Forcementioning

confidence: 99%

Tactile perception of ultrasound

Dalecki

Child²,

Raeman³

et al. 1995

The Journal of the Acoustical Society of America

129

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“…Adequate theoretical description of the radiation force phenomenon has proved to be complicated and has been the subject of controversy (Rooney & Nyborg 1972;Livett et al 1981). This complexity has led many to restrict consideration to linear, plane-wave approximations, but there is reason to believe that their applicability should extend into the transducer's near-field.…”

Section: Radiation Force Measurementsmentioning

confidence: 99%

Detection and Measurement of Acoustic Fields

Hill

2004

Physical Principles of Medical Ultrasonics

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“…66,67 Acoustic radiation force is a body force generated by a transfer of momentum from the acoustic field to the tissue. 80 In acoustic radiation force elastography, a high-intensity (~1 kW/cm 2 ) ultrasound pulse (on the order of 100-μs durations) is typically used to create the acoustic radiation force, resulting in tissue displacements of ~1-20 μm. 67,70,81 After application of the radiation force, tissue deformation (i.e., displacement) associated with shear wave propagation is monitored spatially over time using conventional pulse-echo ultrasound.…”

Section: Elastographymentioning

confidence: 99%

Quantitative Ultrasound for Nondestructive Characterization of Engineered Tissues and Biomaterials

2015

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Non-invasive, non-destructive technologies for imaging and quantitatively monitoring the development of artificial tissues are critical for the advancement of tissue engineering. Current standard techniques for evaluating engineered tissues, including histology, biochemical assays and mechanical testing, are destructive approaches. Ultrasound is emerging as a valuable tool for imaging and quantitatively monitoring the properties of engineered tissues and biomaterials longitudinally during fabrication and post-implantation. Ultrasound techniques are rapid, non-invasive, non-destructive and can be easily integrated into sterile environments necessary for tissue engineering. Furthermore, high-frequency quantitative ultrasound techniques can enable volumetric characterization of the structural, biological, and mechanical properties of engineered tissues during fabrication and post-implantation. This review provides an overview of ultrasound imaging, quantitative ultrasound techniques, and elastography, with representative examples of applications of these ultrasound-based techniques to the field of tissue engineering.

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Acoustic Radiation Pressure in a Traveling Plane Wave

Cited by 68 publications

References 0 publications

Tactile perception of ultrasound

Tactile perception of ultrasound

Detection and Measurement of Acoustic Fields

Quantitative Ultrasound for Nondestructive Characterization of Engineered Tissues and Biomaterials

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