Acoustic Measures of Phonation during Connected Speech in Adductor Spasmodic Dysphonia

Cannito, Michael P.; Buder, Eugene H.; Chorna, Lesya; Dressler, Richard

doi:10.4172/2161-119x.s1-003

Cited by 6 publications

(4 citation statements)

References 27 publications

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“…The amount and number of voice breaks in our normal group were zero, unlike the patient group who obviously had voice breaks. Some researchers believe that voice breaks are one of the main characteristics of spasmodic dysphonia (Sebastian, Gowri, 2014;Dejonckere, Manfredi, 2011 ) and others recognize it as a diagnostic strategy for voice disorders (Dejonckere et al, 2001;Cannito, Buder, Chorna, Dressler, 2012). Consistent with our results, Nicola et al (2006) illustrated that voice break in patients were 27, while it was zero in healthy voice.…”

Section: Resultssupporting

confidence: 91%

Acoustic Parameters in Persian-Speaking Patients with Dysphonia

et al. 2018

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Section: Resultssupporting

confidence: 91%

Acoustic Parameters in Persian-Speaking Patients with Dysphonia

et al. 2018

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“…In addition, data from disordered speakers are needed to determine if glottal kinematics can be aligned with the acoustic signal. As previous research indicates, 41,42 voice disorders may result in aperiodic signals that would make it difficult to determine voicing onset from the acoustic wave. These obstacles need to be evaluated and overcome to be able to apply the current data in clinical practice.…”

Section: Discussionmentioning

confidence: 99%

Relationship Between Acoustic Voice Onset and Offset and Selected Instances of Oscillatory Onset and Offset in Young Healthy Men and Women

2017

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Objective To investigate the relationship between (1) onset of the acoustic signal and pre-phonatory phases associated with oscillatory onset and (2) offset of the acoustic signal with the post-phonatory events associated with oscillatory offset across vocally healthy adults. Subjects and Methods High-speed videoendoscopy was captured simultaneously with the acoustic signal during repeated production of /hi.hi.hi/ at typical pitch and loudness from 56 vocally healthy adults (age 20–42 years; 21 male, 35 female). The relationship between the acoustic sound pressure signal and oscillatory onset /offset events from the glottal area waveforms (GAW), were statistically investigated using a multivariate linear regression analysis. Results The onset of the acoustic signal (X1a) is a significant predictor of the onset of first oscillations (X1g) and onset of sustained oscillations (X2g). X1a as well as gender are significant predictors of the first instance of medial contact (X1.5g). The offset of the acoustic signal (X2a) is a significant predictor of the first instance of oscillatory offset (X3g), first instance of incomplete glottal closure (X3.5g), and cessation of vocal fold motion (X4g). Conclusions The acoustic signal onset is closely related to the first medial contact of the vocal folds but the latency between these events is longer for females compared to males. The offset of the acoustic signal occurs immediately after incomplete glottal adduction. The emerging normative group latencies between the onset/offset of the acoustic and the GAW from this study appear promising for future investigations.

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“…For future trials, we suggest using patient perception tests rather than investigator perception tests as the primary outcome. Additional studies of acoustic measurements like vocal spectrograms may provide a reliable objective outcome measure [28]. The fact that patients can be blinded to whether their DBS therapy is "on" or "off" during a trial may add more convincing proof to studies evaluating subjective outcomes.…”

Section: Limitations and Future Considerationsmentioning

confidence: 99%

Deep Brain Stimulation for Spasmodic Dysphonia: A Blinded Comparison of Unilateral and Bilateral Stimulation in Two Patients

Krüger

Honey

2020

Stereotact Funct Neurosurg

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Deep brain stimulation (DBS) is a promising new therapy for patients with spasmodic dysphonia (SD). The preliminary results from our randomized controlled trial showed good clinical effects with unilateral left thalamic stimulation in 6 righthanded patients. This suggests that the pathological process underpinning SD may have a "hemisphere dominant" pathway. We describe 2 patients with concurrent essential tremor and SD who had previously undergone bilateral thalamic DBS for their limb tremor. Both patients experienced an unanticipated improvement of their SD symptoms. One patient was right-handed, and the other was mixed left-handed. To investigate the amount of SD improvement following DBS therapy in each hemisphere, 4 different settings were tested: both sides on, left side on, right side on, and both sides off. Both patients most improved following bilateral stimulation. There was, however, a powerful unilateral benefit in both patients with only a small additional benefit from bilateral stimulation. The right-handed patient improved most with left-hemisphere stimulation whereas the mixed left-handed patient improved most with right hemisphere stimulation. There was some discrepancy between the two tests applied in the second patient reflecting the known difficulties to evaluate vocal symptom improvement in SD. We discuss the possible correlation of handedness and speech hemisphere dominance as well as the need for more reliable tests to measure SD severity. Ultimately, we recommend a bilateral approach for future studies, using a patient perception test as the primary outcome and functional imaging to further investigate the correlation of handedness and the amount of hemisphere dominance in SD.

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Acoustic Measures of Phonation during Connected Speech in Adductor Spasmodic Dysphonia

Cited by 6 publications

References 27 publications

Acoustic Parameters in Persian-Speaking Patients with Dysphonia

Acoustic Parameters in Persian-Speaking Patients with Dysphonia

Relationship Between Acoustic Voice Onset and Offset and Selected Instances of Oscillatory Onset and Offset in Young Healthy Men and Women

Deep Brain Stimulation for Spasmodic Dysphonia: A Blinded Comparison of Unilateral and Bilateral Stimulation in Two Patients

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