“…BSS Plus thus provides only partial protection from corneal damage by the antioxidative properties of GSSG and dextrose. As demonstrated in an in vitro study 49 and confirmed in the present in vivo study, the concentration of 10 À4 M GSSG, as in BSS Plus, is too low to eliminate the adverse effects of hydroxyl radicals. As anticipated from our previous in vitro data, the GSSG 10 À3 M group, with a mean cellular loss of 5.2%, provides better protection than the BSS Plus solution, indicating a direct correlation of endothelial cell protection with the concentration of antioxidants in the irrigating solution.…”