Acoustic angiography: a new high frequency contrast ultrasound technique for biomedical imaging

Abstract

Acoustic Angiography is a new approach to high-resolution contrast enhanced ultrasound imaging enabled by ultrabroadband transducer designs. The high frequency imaging technique provides signal separation from tissue which does not produce significant harmonics in the same frequency range, as well as high resolution. This approach enables imaging of microvasculature in-vivo with high resolution and signal to noise, producing images that resemble x-ray angiography. Data shows that acoustic angiography can provide important information about the presence of disease based on vascular patterns, and may enable a new paradigm in medical imaging.