Acod1 Mediate Anti-inflammatory Treg Function in Sepsis
Michel-Edwar Mickael,
Norwin Kubick,
Atanas G. Atansov
et al.
Abstract:Sepsis is a serious disease that can lead to mortality. The etiology of the disease is connected to how the body as a host reacts toward microbes such as bacteria, viruses, and fungi invasion. Current research shows that during sepsis, the reaction toward microbe attacks takes two main phases. The first is known as a cytokine storm, while the second is a vicious cycle of pro-inflammatory responses followed by a strict anti-inflammatory response led by CD4+ Tregs. Various immunomodulatory therapies have been pr… Show more
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