Ackee Fruit Poisoning: An Outbreak Investigation in Haiti 2000–2001, and Review of the Literature

Joskow, Renée; Belson, Martin; Vesper, Hubert W.; Backer, Lorraine C.; Rubin, Carol

doi:10.1080/15563650600584410

Cited by 73 publications

(53 citation statements)

References 32 publications

(32 reference statements)

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“…In fatal cases, death usually occurs within 48 hours of ingestion. 5,6 Hypoglycemia, hepatic injury, and aciduria have been found to accompany the clinical manifestations. 5 Hassel and Reyle in 1954 first isolated the two toxic constituents, hypoglycin A and B from the arils and seeds of the unripe ackee, respectively.…”

Section: Discussionmentioning

confidence: 99%

Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness

Katibi¹,

Olaosebikan²,

Abdulkadir³

et al. 2015

The American Society of Tropical Medicine and Hygiene

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Abstract. Ackee apple fruit is a native fruit to Jamaica and some parts of west Africa. Its toxicity known as "Jamaican vomiting sickness" dates back to the nineteenth century. However, there is a dearth of reported published data on toxicity from Nigeria where it is popularly known in the southwest as "ishin." We report a case series of eight previously well Nigerian siblings who presented at various intervals after ingestion of roasted seeds and aril of the ackee fruit.

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Section: Discussionmentioning

confidence: 99%

Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness

Katibi¹,

Olaosebikan²,

Abdulkadir³

et al. 2015

The American Society of Tropical Medicine and Hygiene

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“…The ackee is also considered as one of the national symbols in Jamaica. Although an extensive literature exists on the toxicity of hypoglycin A [3][4][5][6], there is no referenced data reporting the physiology and biochemistry of ackee fruit during storage except that reported by Benkeblia [7].…”

Section: Introductionmentioning

confidence: 99%

Effects of modified atmosphere packaging (MAP) on microbiological and sensory quality of ackee fruit arils (Blighia sapida Köenig) stored under refrigerated regimes

Morgan¹,

Benkeblia²

2017

Packaging Research

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Abstract:In this study, we investigated the effects of two modified atmosphere packaging films [Osmolux (Osx) and Oriented PolyPropylene (OPP)] on the microbiological and the sensory qualities of ackee fruit (Blighia sapida Köenig) arils stored during eight days under two refrigerated temperatures, 5 ±1°C and 10 ±1°C. The control samples of ackee arils were packaged in a macro-perforated highdensity polypropylene film (MP). The results showed that mesophilic aerobic bacteria (MAB), yeasts and moulds were lower under OPP, although MAB of MP was lower at 5°C. At 10°C, the pH of the ackee arils stored in Osx and OPP did not vary significantly, but the pH of MP showed an increase from 5.32 to 5.95 and 5.83 at 5°C and 10°C, respectively. Results also showed that under OPP, weight losses were lower and averaged 0.12 % and 0.19 % after eight days storage at 5°C and 10°C, respectively, while the sensory quality attributes were preserved up to six days. Conclusively, OPP showed better attributes for MAP storage of ackee arils under refrigerated temperatures, although none of the two films were effective to reduce the chilling injury after the eight days storage.

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“…The fruit splits open while still on the tree to reveal 3glassy black seeds surrounded by a thick, oily, yellow aril. An association between ackee poisoning and Jamaican vomiting sickness was made in 1875 with a water-soluble toxic material in the seed and pods of the ackee fruit (Joskow et al, 2006;Moya, 2001;Gaillard et al, 2011). Hassal and Reyle (1954) were the first to isolate two toxic compounds in their crystalline form from the unripe fruit and the compounds were called hypoglycin A and B because of their hypoglycemic activity.…”

Section: Introductionmentioning

confidence: 99%

Isolation, partial purification and characterization of antifungal trypsin inhibitor protease from the seed of Blighia sapida K.D. Koenig (Ackee)

Nwozo¹,

Iwuoha²,

Waryo³

et al. 2014

Afr. J. Biotechnol.

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Seed proteins have been evaluated for their nutritive value and biological activity. Proteases and proteinase inhibitors have been of immense benefit to both agriculture and therapeutic purposes. The seed proteins of Blighia sapida was evaluated for both structure and biological activity in this study. The matured dried seeds were pulverized and sequentially extracted using 10 mM Tris/HCl pH 7.4, 10 mM ammonium acetate and 10 mM sulphuric acid. Crude protein extracts were concentrated and the protein concentrations were estimated. Proteins were purified by 70% ammonium sulphate precipitation, Sephadex G50 reversed phase chromatography and finally by HPLC on a C18 column. Two bands were obtained from SDS-PAGE electrophoresis and they were identified by ESI/MS using in gel tryptic digestion. The seed protein from B. Sapida consists of two single polypeptide chains each with mass of about 24 to 27 KDa as established by a combination of SDS-PAGE and ESI/MS. Proteins exhibited protease activity, which was confirmed by zymography. Protease activity was characterized for effect of temperature, pH, divalent metal ions and chelating agents. The crude protein from the seed of B. sapida showed antimicrobial activity and the antifungal activity was comparable with the reference drug, Ticonazole.

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Ackee Fruit Poisoning: An Outbreak Investigation in Haiti 2000–2001, and Review of the Literature

Cited by 73 publications

References 32 publications

Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness

Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness

Effects of modified atmosphere packaging (MAP) on microbiological and sensory quality of ackee fruit arils (Blighia sapida Köenig) stored under refrigerated regimes

Isolation, partial purification and characterization of antifungal trypsin inhibitor protease from the seed of Blighia sapida K.D. Koenig (Ackee)

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