Acinetobacter baumannii infection in patients with hematologic malignancies in intensive care unit: Risk factors and impact on mortality

Risk factors for acquisition of multidrug-resistant Acinetobacter baumannii among cancer patients

“…16 Previous studies reported that presence of immunosuppressive therapy or type of malignancy was not independently associated with ICU-acquired infections. 17,18 The risk factors for acquisition of MDR A baumannii identified in our study are similar to the risk factors identified among the general ICU population. MDR A baumannii acquisition among patients with cancer thus seems to be more associated with general nosocomial infection risk factors rather than their underlying malignancies.…”

Intensive care unit-acquired Acinetobacter baumannii infections in a Moroccan teaching hospital: epidemiology, risk factors and outcome

“…6, [16][17][18][19][20][21] Our findings show that patients who spent 14 days or more in the ICU had over six-fold increased risk of ICU-acquired A. baumannii infections, suggesting that ICU-acquired A. baumannii infections are due to prolonged ICU stay. Moreover, the median length of ICU stay of patients who developed ICU acquired A. baumannii infection was longer than that of other patients (18 (IQR: 10-26) days vs. 3 (IQR: 1-6) days, p<0.0001) in this study, testifying that these infections were also responsible for a significantly longer ICU stay.…”

“…32 The independent predictors of mortality reported in previously published studies and which were not identified in our study were: length of ICU stay, duration of intubation, inappropriate use of antibiotics after diagnosis of the infection, presence of malignancy, need for mechanical ventilation, resistance to carbapenems, recent surgery, acute respiratory failure and acute renal failure. [8][9][10][11]14,16,19,23 …”

Predictors of 7- and 30-day mortality in pediatric intensive care unit patients with cancer and hematologic malignancy infected with Gram-negative bacteria

“…1 With recent advances in cancer treatments and improvements in critical care, an increasing number of patients with hematologic malignancies are being admitted to intensive care units (ICU). 2 Despite the associated improvements in outcomes, mortality remains high in critically ill patients with hematologic malignancies, particularly in the presence of ICUacquired nosocomial infections. 2 In addition, infection results in ICU admission in cancer patients.…”