Acinetobacter: an old friend, but a new enemy

Mortality risk factors in burn care units considering the clinical significance of acinetobacter infections

“…Majority of the clinical isolates were susceptiple to most antimicrobials in earlier periods; however, multi-drug resistant isolates have emerged due to extensive use of broad spectrum agents worldwide. [4] Our results revealed that MDR rates were also associated with increased mortality, not emerging as an underlying risk factor. Of the thirty-three patients with Acinetobacter, twenty-nine of them and of the twenty-seven patients with P. aeruginosa, nineteen of them represented MDR.…”

“…Of special concern, Acinetobacter isolates have been increasingly reported in recent years and have emerged as a significant nosocomial pathogen. [4] The most common microorganism isolated was A. baumannii in our study. As a high prevalance, 33.6% was in concordance with some reports.…”

“…[3] Due to the increased rate of worldwide resistance and infections, Acinetobacter isolates represent a challenge in the treatment of burns. [4] The data of a total of four hundred and sixty five patients in our burn care unit were reviewed and patients' characteristics and outcome including burn data, infections encountered, pathogens and antibiotic susceptibility tests, infections caused by resistant organisms, risk factors for mortality, and the role of Acinetobacter isolates in mortality were evaluated.…”

Diversity Within the O-linked Protein Glycosylation Systems of Acinetobacter Species

“…The growing number of identified multiple drug resistant (MDR) 1 strains (2-4), the ability of isolates to rapidly acquire resistance (3,4), and the propensity of this agent to survive harsh environmental conditions (5) account for the increasing number of outbreaks in intensive care, burn, or high dependence health care units since the 1970s (2)(3)(4)(5). The burden on the global health care system of MDR A. baumannii is further exacerbated by standard infection control measures often being insufficient to quell the spread of A. baumannii to high risk individuals and generally failing to remove A. baumannii from health care institutions (5). Because of these concerns, there is an urgent need to identify strategies to control A. baumannii as well as understand the mechanisms that enable its persistence in health care environments.…”

Characterization and Determination of Antibiotic Resistance Profiles of a Single Clone Acinetobacter baumannii Strains Isolated from Blood Cultures

“…Çok ilaca dirençli (ÇİD) A.baumannii suşları özellikle immün sistemi baskılanmış, ventilatöre bağımlı veya deri bütünlüğü bozulmuş hastala rın izlendiği yoğun bakım ve yanık ünitelerinde görülen hastane enfeksiyonu etkenleri arasında ilk sıralara yerleşmiştir 9,17,18 . Epidemiyolojik çalışmalarda salgınlara yol açan ÇİD A.baumannii suşlarının yayılımında hastanedeki kontamine yüzeyler bu patojen için önemli bir rezervuardır 19,20 .…”