Acidity and photolability of ruthenium salen nitrosyl and aquo complexes in aqueous solutions

Bordini, Jeane; Novaes, D.O.; Borissevitch, Iouri; Owens, Bridget; Ford, Peter C.; Tfouni, Elia

doi:10.1016/j.ica.2007.11.018

Cited by 25 publications

(21 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…25,42 As in the case of the latter two complexes and others, such as trans-[Ru(salen) (NO)(OH 2 )] + with a pK a of 4, 40 it indicates a strong Ru III character. 6 ) 3 when it is submitted to a controlled potential electrolysis at -500 mV vs. Ag/AgCl in acetonitrile (m = 0.1 mol L -1 tba(PF 6 )) are shown in Figures 5 and 6.…”

Section: The Cyclic Voltammetry Study Of Trans-[ru(no)mentioning

confidence: 94%

“…Among the NO donors, ruthenium nitrosyl complexes are particularly attractive because they are stable, can be either water soluble or not, deliver NO at different rates upon activation by reduction at biologically accessible potentials and/or by light irradiation, in either solution or matrices. [14][15][16][17][18]34,[40][41][42][43][44][45][46][47][48][49] These properties can be tuned by the adequate choice of ligands. 14,18 It should be pointed out that interesting biological activities for several of these complexes have already been reported.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chemical and photochemical properties of a ruthenium nitrosyl complex with the N-monosubstituted cyclam 1-(3-Propylammonium)-1,4,8,11-tetraazacyclotetradecane

Ferreira¹,

Tfouni²

2010

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

O complexo aminofuncionalizado trans-[Ru(NO)Cl(1-pramcyH)](PF 6 ) 3 (1-pramcyH = 1-(3-propilamônio)-1,4,8,11-tetraazaciclotetradecano) foi sintetizado através da reação do trans-[RuCl(tfms)(1-pramcyH)](tfms) 2 (tfms = trifluorometanossulfonato) com óxido nítrico (NO) em solução aquosa ácida. O complexo foi caracterizado por análise elementar, espectroscópica (UVvis, IV, RMN de 1 H e 13 C) e eletroquímica. Dois valores de pK a (7,0 e 8,2) foram determinados para trans- [Ru(NO) ](PF 6 ) 3 e foram atribuídos a um dos prótons do grupo amina do cyclam e ao propilamônio. A redução do trans- [Ru(NO) ] 3+ leva à saída rápida de cloreto seguida de saída lenta de NO, enquanto a irradiação do complexo em solução aquosa desaerada resulta na labilização fotoquímica do NO. O rendimento quântico para a fotoaquação do NO diminui com o aumento do comprimento de onda de irradiação e com a diminuição do pH, e é observável apenas a l irr < 370 nm. O comportamento do trans- [Ru(NO) ] 3+ é semelhante ao do complexo análogo trans- [Ru(NO) Cl(cyclam)] 2+ , porém difere daquele do complexo com carboxipropil como substituinte.The amine-functionalized trans- [Ru(NO) ](PF 6 ) 3 complex (1-pramcyH = 1-(3-propylammonium)-1,4,8,11-tetraazacyclotetradecane) was synthesized from trans- [RuCl(tfms) (1-pramcyH)](tfms) 2 (tfms = trifluoromethanesulfonate) in acidic aqueous solution in the presence of nitric oxide (NO). The complex was characterized by elemental, spectroscopic (UV-Vis, IR, 1 H and 13 C NMR) and electrochemical analyses. Two pK a values (7.0 and 8.2) were estimated for trans- [Ru(NO) ](PF 6 ) 3 and were assigned to one of the cyclam nitrogen protons and to the protonated aminopropyl group. Reduction of trans- [Ru(NO) ] 3+ results in rapid loss of chloride followed by slower loss of NO, while irradiation of the complex in aqueous deaerated conditions suggests photochemical labilization of NO. The quantum yields for NO photoaquation decrease as the irradiation wavelength increases, being noticeable only at l irr < 370 nm, and increase as pH increases. The behavior of trans- [Ru(NO) ] 3+ , which contains an aminopropyl substituted cyclam, parallels that reported for the analogous complex with the unsubstituted ligand, but differs from that described for the complex in which carboxypropyl is the substituent. Keywords: nitrosyl, ruthenium, nitric oxide donor, substituted cylam, mono-N-functionalized cyclam IntroductionThe discovery of the participation of nitric oxide (NO) in a wide range of physiological processes and pathologies 1 has launched investigations on NO donors, including metal nitrosyl complexes in solution or immobilized in matrices, aiming at the understanding of both fundamental aspects and biological activity for potential applications. Among the NO donors, ruthenium nitrosyl complexes are particularly attractive because they are stable, can be either water soluble or not, deliver NO at different rates upon activation by reduction at biologically accessible Chemical and Photochemical Properties of a Ruthenium Nitrosyl...

show abstract

Section: The Cyclic Voltammetry Study Of Trans-[ru(no)mentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Chemical and photochemical properties of a ruthenium nitrosyl complex with the N-monosubstituted cyclam 1-(3-Propylammonium)-1,4,8,11-tetraazacyclotetradecane

Ferreira¹,

Tfouni²

2010

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

show abstract

“…When bound to a metal center, nitric oxide can either accept or donate electron density from or to the metal ( Figure 4 properties that indicate the bond order for NO to be greater than that of N=O. [61][62][63][64][65][66][67][68].…”

Section: Metal Nitrosylsmentioning

confidence: 99%

Photo-Controlled Release of NO and CO with Inorganic and Organometallic Complexes

Pierri

Muizzi

Ostrowski

et al. 2014

Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents

View full text Add to dashboard Cite

Abstract:The photochemical delivery of bioactive small molecules to physiological targets provides the opportunity to control the location, timing and dosage of such delivery. We will discuss recent developments the synthesis and studies of various metal complexes designed for targeted release of the bioregulatory diatomics nitric oxide and carbon monoxide. Of considerable interest are those systems where the NO or CO precursor and/or the photochemical product is luminescent such that imaging techniques allow one to identify the release location.

show abstract

“…142 13 Outros ligantes -receptores, tais como: CO e isn, também aumentam a acidez do ligante trans-H2O coordenado ao Ru(II) quando comparamos com [Ru(H2O)(NH3)5(H2O)] 2+ . 11 O complexo com cyclam apresenta um comportamento parecido com as tetraaminas (pKa ~3) 21 .…”

Section: -7 Espectroscopia De Ressonância Paramagnética De Elétrounclassified

“…11 O complexo com cyclam apresenta um comportamento parecido com as tetraaminas (pKa ~3) 21 . A presença do ligante salen no plano equatorial resulta em uma trans-H2O menos ácida que outros complexos nitrosilos (pKa ~4,5) 13 (1,4,8,11-…”

Section: -7 Espectroscopia De Ressonância Paramagnética De Elétrounclassified

Síntese, caracterização e reatividade química de complexos de cloro e nitrosil de trans-Tetrakispiridina de rutênio

Calandreli¹

View full text Add to dashboard Cite

show abstract

Acidity and photolability of ruthenium salen nitrosyl and aquo complexes in aqueous solutions

Cited by 25 publications

References 61 publications

Chemical and photochemical properties of a ruthenium nitrosyl complex with the N-monosubstituted cyclam 1-(3-Propylammonium)-1,4,8,11-tetraazacyclotetradecane

Chemical and photochemical properties of a ruthenium nitrosyl complex with the N-monosubstituted cyclam 1-(3-Propylammonium)-1,4,8,11-tetraazacyclotetradecane

Photo-Controlled Release of NO and CO with Inorganic and Organometallic Complexes

Síntese, caracterização e reatividade química de complexos de cloro e nitrosil de trans-Tetrakispiridina de rutênio

Contact Info

Product

Resources

About