Acidic Pepsin Affects Laryngeal Carcinoma Cell Growth and Invasion Through Glycolysis
Ding‐Li Yu,
Ke‐Da Li,
Yang‐Yang Bao
et al.
Abstract:ObjectiveThe pathogenic mechanism underlying the effects of acidic pepsin in laryngeal cancer remains unclear. This study investigated whether acidic pepsin influences Glut‐1 expression and glycolytic activity in laryngeal carcinoma cells and whether it plays a role in the growth and migration of these cells through glycolysis.Study DesignIn vitro study.SettingA university‐affiliated hospital.MethodsLaryngeal carcinoma TU 212 and TU 686 cells were treated with acidic pepsin and 2‐deoxy‐d‐glucose (2‐DG), then t… Show more
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