Acid-triggered two-stage superlarge redshift absorption for turn-on type photothermal conversion at the first and second near-infrared window

Abstract

Benefiting from the deeper tissue penetration and the higher allowed maximum exposure power, near infrared (NIR)-II (1000-1350 nm) absorbers for photothermal conversion have received considerable attentions in myriad fields. To...

NIR-II Ratiometric Fluorescence Probes Enable Precise Determination of the Metastatic Status of Sentinel Lymph Nodes

“…Fluorescence imaging in the NIR-II window (900–1700 nm) offers promising quality for imaging deep biological tissues with high signal-to-background ratios. − Many studies have utilized fluorophores that emit in the NIR-II window to intravitally image sentinel lymph nodes and perform imaging-guided dissection of tumor cells-draining LNs. ,,− A representative work utilized a multiplexed NIR-II imaging system to visualize the primary tumor by tumor-accumulating organic small fluorophore, accompanied by using ultrabright quantum dots to light up the cancer-invaded SLNs . The nonoverlapping dual-channel imaging approach with high imaging contrast enables precise imaging-guided excision of tumor-draining SLNs, alleviating intraoperative invasion and facilitating postoperative recovery .…”