Acid-Suppressive Medication and Hospital-Acquired Pneumonia

Impact of proton pump inhibitor use on magnesium homoeostasis: a cross-sectional study in a tertiary emergency department

“…PPI are generally well tolerated, and with more than 100 million prescriptions each year in the US , they are among the highest‐selling drugs worldwide. Although the evidence for adverse events related to the use of PPI is limited by the absence of randomised controlled trials, there is concern that overprescribing may potentially contribute to bone fractures , pneumonia , Clostridium difficile infection , among other conditions and thus lead to escalating healthcare expenditure .…”