2003
DOI: 10.1016/s0142-9612(02)00576-8
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Acid pretreatment of titanium implants

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Cited by 104 publications
(76 citation statements)
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“…Acid treatment of the surfaces of titanium implants results in uniform roughness with micro pits ranging in size from 0.5-2 µm, increase in surface area, and an improvement in bioadhesion. Acid treatment of implants enhances osseointegration as these implants can facilitate migration and retention of osteogenic cells at the implant surface (Takeuchi et al, 2003). Alkali treatment involves immersion of the implants in either sodium or potassium hydroxide followed by heat treatment by rinsing in distilled water.…”
Section: Chemical Methodsmentioning
confidence: 99%
“…Acid treatment of the surfaces of titanium implants results in uniform roughness with micro pits ranging in size from 0.5-2 µm, increase in surface area, and an improvement in bioadhesion. Acid treatment of implants enhances osseointegration as these implants can facilitate migration and retention of osteogenic cells at the implant surface (Takeuchi et al, 2003). Alkali treatment involves immersion of the implants in either sodium or potassium hydroxide followed by heat treatment by rinsing in distilled water.…”
Section: Chemical Methodsmentioning
confidence: 99%
“…This protective layer in bone can grow in thickness and facilitate ion exchange, however, the low rate of dissolution and the chemical inertness of Ti dissolution products allow bone to thrive and osteointegrate with Ti [7] . Studies by Takadama et al has found…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, a great deal of carbon contamination was detected in RGD/Ti relative to P-Ser/Ti and P-RGD/Ti ( Table 2). The HCl-based decontamination method used in this study 19) should facilitate stable chemical modification of the Ti surface and promote progressive binding of amino acids to the modified surface. On this note, Krozer et al 20) reported that the bonding of amino-alcohol, used for cleaning contaminated implant surfaces, was stronger to an acid-treated Ti surface than to an anodically oxidized Ti surface.…”
Section: Resultsmentioning
confidence: 99%
“…Five pure titanium disks (diameter: 5.8 mm, thickness: 2 mm; JIS 2; GC, Tokyo, Japan) for each compound were cleaned by ultrasonic treatment with 10 N HCl (Katayama Chemical, Osaka, Japan) for 30 min, followed by ultrasonic rinsing with ultrapure water (MilliQ water: >18 MΩcm) for another 30 min 19) . These disks were then immersed in either 50 mM P-RGD, 50 mM RGD or 50 mM P-Ser at 37°C for 12 h. The disks exposed to P-RGD, RGD and P-Ser individually (P-RGD/Ti, RGD/Ti and P-Ser/Ti) were subjected to ultrasonic rinsing with MilliQ water for 10 min.…”
Section: Sample Preparationmentioning
confidence: 99%