Acid-catalyzed oxidation of carboxymethyl cellulose. Kinetics and mechanism of permanganate oxidation of carboxymethyl cellulose in acid perchlorate solutions

Kinetics and mechanism of oxidation of cetirizine hydrochloride, an anti-allergy agent by Mn(VII) in acidic medium

“…The kinetics of oxidation of drug by MnO 4 -in acid medium was studied in temperature range 293K to 313K using Systronic 2202 UV-Vis spectrophotometer equipped with a thermostatic water bath for temperature control (accuracy = 0.1 o C). The pH of the solution was measured using pre-standardized Elico (India) digital pH meter equipped with glass electrode.…”

“…MnO 4 -is a strong oxidant with the standard redox potential (E O ) as 1.51 volt (Atkin et al2012) for the MnO 4 -/Mn 2+ couple. The oxidation state of Mn in the different manganese containing species may vary from +7 to +2 depending upon the nature of the Mn species and pH of the medium.…”

“…The electron transfer reaction of Mn(VII) in acidic medium has been extensively studied (Arrizabalaga et al1996, Hassan et al2009, Zaafarany.2010, Mohanty et al2013)Large biological molecules such as nucleic acid ( Simandanetet al1998), proteins (Terashima etal.1999) ,thymine (Freeman et al1975), Uracil (Freeman et al1981), several amino acids (Mudalior et al1983, Verma et al1976, Perzez et al1987, Zammar et al1992, Timmanagoudar et al1997, Timmanagoudar et al1996 have already been studied. But the oxidation of various water soluble drugs with MnO 4 -has not been carried out. In this paper we present the redox reaction of an anti-allergic drug cetirizine hydrochloride by MnO 4 -.…”

“…But the oxidation of various water soluble drugs with MnO 4 -has not been carried out. In this paper we present the redox reaction of an anti-allergic drug cetirizine hydrochloride by MnO 4 -. This study will show the path how the drug is oxidized under physiological conditions.…”

Kinetics and Mechanism Studies of Oxidation of Dibromothymolsulfonphthalein Toxic Dye by Potassium Permanganate in Neutral Media with the Synthesis of 2-Bromo-6-isopropyl-3-methyl-cyclohexa-2,5-dienone

“…The kinetics and oxidation processes of pectates, 18 methyl cellulose, 19 alginates, 20 carboxymethyl cellulose, 21 chondroitin-4-sulfate 22 carbohydrates, and BTB 23 by potassium permanganate have been studied in basic solutions. However, the oxidation of methyl cellulose, 15 pectates, 24 carboxymethyl cellulose, 25 BTB, 26 N -(2-acetamido)imino diacetic acid, 27 poly(ethylene glycol), 28 2-butanol, 29 , 30 and mannitol 31 were investigated in acidic solutions. In these reactions, the pseudo-first-order plots were discovered to be reverse S-shape, and the reactions were found to proceed through free-radical intervention.…”