Acid-base in dialysis

Feriani, M; Fabris, A; Greca, G. La

doi:10.1007/978-1-4020-2275-3_33

Cited by 2 publications

(3 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chronic metabolic acidosis with variable degree of respiratory compensation is the rule in ESRD patients on maintenance HD; it is temporarily corrected during dialysis by the bicarbonate buffer in the dialysis solution and rapidly returns to predialytic levels before the beginning of subsequent dialysis (5). Patients' respiratory compensation may be further reduced in the presence of established COPD (6).…”

Section: Discussionmentioning

confidence: 99%

Acid‐Base Balance and Oxygen Tension During Dialysis in Uremic Patients With Chronic Obstructive Pulmonary Disease

Manca-di-Villahermosa

Tedesco

Lonzi

et al. 2008

Artificial Organs

View full text Add to dashboard Cite

Recent reports on the effects of dialysis on acid-base balance and metabolic acidosis correction in end-stage renal disease (ESRD) patients with chronic obstructive pulmonary disease (COPD) are lacking. Here, we compared acid-base balance and blood gasses among 14 patients with established COPD (group A) and eight patients with normal respiratory function (group B). The two groups were homogeneous for age, time on dialysis, and male/female ratio. At the beginning of dialysis, acid-base balance and blood gasses were comparable between patients of groups A and B. A significant difference between groups was observed only in pCO(2) at 20 min, together with a delay in pH increase. Effective correction of acidosis was reported at the end of dialysis and is not significantly affected by COPD. Nevertheless, weight loss must be carefully monitored in these patients in order to prevent hyperhydration and worsening of respiratory function.

show abstract

Section: Discussionmentioning

confidence: 99%

Acid‐Base Balance and Oxygen Tension During Dialysis in Uremic Patients With Chronic Obstructive Pulmonary Disease

Manca-di-Villahermosa

Tedesco

Lonzi

et al. 2008

Artificial Organs

View full text Add to dashboard Cite

show abstract

“…[ 9 10 11 12 13 ] The cause of such morbidity is theorized to be a result of acetate accumulation and toxicity, stimulation of interleukin production from monocytes, slow metabolism of acetate to bicarbonate, and acute metabolic acidemia due to bicarbonate removal from the blood space. [ 3 ]…”

Section: Dialysate Buffermentioning

confidence: 99%

“…[ 1 2 ] Additionally, chronic acidemia is associated with a catabolic effect that is theorized to contribute to dysfunctional protein metabolism, malnutrition and aggravation of osteodystrophy secondary to excessive bony buffering of nonvolatile acids. [ 3 ]…”

Section: Introductionmentioning

confidence: 99%

Basics of base in hemodialysis solution: Dialysate buffer production, delivery and decontamination

Desai¹

2015

Indian J Nephrol

View full text Add to dashboard Cite

Hemodialysis requires the use of high volumes of freshly prepared, clean dialysate to foster the removal of low molecular weight metabolites (i.e., urea) and to correct the electrolyte and acid-base imbalance of chronic renal failure. Dialysate is produced by mixing clean, AAMI grade water with both an acid and base concentrate. This purpose of this report is to describe production, mixing and delivery of the buffer component of dialysate, and to also to address the cost, safety and feasibility of producing online bicarbonate. As endotoxin contaminated dialysate has been associated with the release of key mediators in acute and chronic inflammatory diseases associated with long-term hemodialysis therapy, aspects of disinfecting a bicarbonate delivery loop are also addressed.

show abstract

Acid-base in dialysis

Cited by 2 publications

References 92 publications

Acid‐Base Balance and Oxygen Tension During Dialysis in Uremic Patients With Chronic Obstructive Pulmonary Disease

Acid‐Base Balance and Oxygen Tension During Dialysis in Uremic Patients With Chronic Obstructive Pulmonary Disease

Basics of base in hemodialysis solution: Dialysate buffer production, delivery and decontamination

Contact Info

Product

Resources

About