Acid-base equilibrium in Menière's disease

Celestino, D; Cerulli, N.; Iannetti, Giorgio; Sagliaschi, G

doi:10.1017/s0022215100082049

Cited by 10 publications

(3 citation statements)

References 25 publications

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“…Weille (1967) and Celestino et al (1976) have observed an alteration in the acid-base balance, i.e. a metabolic alkalosis, which arises mainly during the acute crisis of the disease.…”

mentioning

confidence: 99%

Plasmatic osmolality in Menière's disease

Celestino¹,

Ralli²

1981

J. Laryngol. Otol.

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“…Weille (1967) and Celestino et al (1976) have observed an alteration in the acid-base balance, i.e. a metabolic alkalosis, which arises mainly during the acute crisis of the disease.…”

mentioning

confidence: 99%

Plasmatic osmolality in Menière's disease

Celestino¹,

Ralli²

1981

J. Laryngol. Otol.

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“…It is possible that underlying physiological differences in patients with Meniere's disease may account for the increased incidence of adverse effects. Thus a systemic abnormality in acid-base balance producing a metabolic alkalosis has been observed (Weille, 1967;Celestino et al, 1976). Other workers have found elevated serum osmolalities in between 22 per cent and 33 per cent of Meniere's patients (Angelborg et al, 1973;Celestino and Ralli, 1980).…”

Section: Discussionmentioning

confidence: 98%

Oral acetazolamide in Menière's disease

Brookes¹,

Booth²

1984

J. Laryngol. Otol.

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The therapeutic efficacy of oral acetazolamide has been evaluated in a small pilot study of 14 patients with Menière's disease (23 hydropic ears). Symptomatic improvement was found in 4 cases. In 2 of these patients the improvement was not sustained, whilst another had to stop the drug due to the development of bilateral renal calculi. A deterioration in symptoms was seen in 3 cases. Significant adverse side-effects were encountered in 6 of the 13 patients (46.2 per cent) who complied with drug dosage instructions. It is suggested that this high incidence of side-effects may be consistent with a general metabolic difference between Menière's patients and normal subjects. We conclude that oral acetazolamide has no place in the medical treatment of Menière's disease.

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“…1 " 4 Takahashi et al 1 described pH, bicarbonate (HC03 -), base excess (BE), and arterial carbon dioxide pressure (PaC02) in 3 cases of Meniere's disease. These 3 cases had metabolic acidosis, and 2 of them also had respiratory acidosis.…”

Section: Introductionmentioning

confidence: 99%

Arterial Blood Gas Abnormalities in Patients with Dizziness

Morinaka¹,

Nakamura²

1998

Ann Otol Rhinol Laryngol

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Arterial blood gases were analyzed in 121 patients with dizziness. Sixty-one showed arterial blood gas abnormalities in the dizziness period. An increase in bicarbonate was seen in 57, increases in both bicarbonate and arterial carbon dioxide pressure in 8, and a low arterial oxygen pressure in 22 patients. The frequency of the abnormalities was significantly higher in those with central-peripheral diseases than in those with Meniere's disease. Arterial blood gases were also checked at random in the remission period in 22 patients. The frequency of dizziness recurrence was significantly higher in patients with the abnormalities in the remission period than in patients without them. These results indicate that approximately half of the patients with dizziness tend to have arterial blood gas abnormalities in the dizziness period. It is suggested that arterial blood gas abnormalities cause temporary vestibular dehabituation that increases the frequency of dizziness in central-peripheral diseases and Meniere's disease.

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Acid-base equilibrium in Menière's disease

Cited by 10 publications

References 25 publications

Plasmatic osmolality in Menière's disease

Plasmatic osmolality in Menière's disease

Oral acetazolamide in Menière's disease

Arterial Blood Gas Abnormalities in Patients with Dizziness

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