Achilles Tendon Thickness of Familial and Secondary Hypercholesterolemic Patients

Characteristic Features of Long‐Living Patients with Familial Hypercholesterolemia in Japan

“…Figure 3 shows the relationship between Δ serum total cholesterol (serum total cholesterol (mg/dL)–250) X age (in years) and Δ Achilles tendon thickness (Achilles tendon thickness (mm) −7.5). The value of 7.5 mm is the upper limit of Achilles tendon thickness of normal Japanese 13 . The correlations of these two indices, A serum total cholesterol X age as x , and Δ Achilles tendon thickness as y , were y = 0.001009 x + 1.323, r = 0.648, P < 0.01 in males and y = 0.000373 x + 2.251, r = 0.408, P < 0.01 in females (Figure 3).…”

“…Mabuchi et al 3 reported that the age at death from myocardial infarction was 58 ± 13 years in male FH heterozygotes and 69 ± 8 years in female FH heterozygotes in the Japanese population; these incident ages are less than the average life span (males, 75 years; females, 80 years) 13 . This fact seems to explain the constantly lower ratios in the FH heterozygotes after their 50's in males and 60's in females compared with the corresponding ratios in the general population.…”