Achilles Tendon Thickness Is an Independent Predictor of Carotid Atherosclerosis and Is Associated With a Carotid Plaque Burden

Генкель, В. В.; Кузнецова, А. С.; Lebedev, E. V.; Синицкий, А. И.; Pykhova, Lubov; Шапошник, И. И.

doi:10.1177/0003319720928226

Cited by 6 publications

(5 citation statements)

References 24 publications

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“…[20][21][22][23][24] Data initially obtained from a population of patients with FH, concerning the ability of ATT to be used to make a representative measurement of the severity of coronary atherosclerosis, has been replicated in the past few years in populations of patients without FH and other vascular beds. [3][4][5] The main findings of the study being presented here are as follows: 1) patients with asymptomatic PAD possessed statistically significant higher values of ATT (p = .049), ATT/BSA (p = .002), ATW/BSA (p < .01), AT CSA/BSA (p = .003) in comparison with the control group and 2) according to the results of ROC-analysis, the diagnostic performance of AT sizes, after their normalization to BSA, increased significantly (in AUC and the Youden index). The ATT/BSA (Du Bois) had the highest diagnostic value; an increase of >0.29 cm/m 2 allowed for the prediction of the presence of asymptomatic PAD with a sensitivity of 61.1% and a specificity of 77.9%.…”

Section: Discussionmentioning

confidence: 99%

“…20–24 Data initially obtained from a population of patients with FH, concerning the ability of ATT to be used to make a representative measurement of the severity of coronary atherosclerosis, has been replicated in the past few years in populations of patients without FH and other vascular beds. 3–5…”

Section: Discussionmentioning

confidence: 99%

“…We have previously demonstrated that ATT directly correlates with the degree of carotid artery stenosis and the burden of carotid atherosclerosis, and also allows for the prediction of the presence of carotid plaque with a sensitivity of 68.3% and a specificity of 62.5%. 5 Thus, ATT is a promising marker of atherosclerotic cardiovascular disease (ASCVD). In addition, research is underway aimed at finding new markers associated with the assessment of AT (e.g.…”

Section: Introductionmentioning

confidence: 99%

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Achilles tendon thickness normalized to body surface area as a marker of asymptomatic peripheral arterial disease

et al. 2022

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Objectives The normalisation of Achilles tendon thickness (ATT) to anthropometric parameters may increase the diagnostic efficiency of the assessment of ATT. The aim of this study was to compare the diagnostic value of AT dimensions depending on their normalization to body surface area (BSA) in patients with asymptomatic peripheral arterial disease (PAD). Methods All patients underwent duplex scanning of the carotid arteries and the lower limb arteries. Asymptomatic PAD was defined as the presence of ≥50% stenosis in the carotid and/or lower limb arteries. ATT was measured using a longitudinal scan, width (ATW) and cross-sectional area (AT CSA), which was determined during a cross-sectional scan. Results The study included 369 patients, among whom asymptomatic PAD was detected in 18 (4.88%) patients. Only the ATT demonstrated diagnostic value for asymptomatic PAD. After normalizing the size of the AT to the BSA, the diagnostic performance of ATT, ATW and AT CSA became statistically significant. Among the studied parameters, only an increase in ATT/BSA >0.29 cm/m2 was associated with a significant increase in the odds ratio (OR) of asymptomatic PAD by 4.11 times (95% CI 1.08–15.7; p = .038) after adjustments. Conclusion An increase in ATT/BSA >0.29 cm/m2 predicted the presence of asymptomatic PAD with a sensitivity of 61.1% and a specificity of 77.9%. ATT/BSA values of less than 0.29 cm/m2 made it possible to exclude asymptomatic PAD with a probability of 97.5%. An increase in ATT/BSA >0.29 cm/m2 was associated with a 4.11-fold increase in the OR of asymptomatic PAD (95% CI 1.08–15.7).

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Achilles tendon thickness normalized to body surface area as a marker of asymptomatic peripheral arterial disease

et al. 2022

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“…The percentage of stenosis was measured planimetrically in B-mode according to the diameter in the cross-section of the vessel with the percentage of stenosis being determined according to the European Carotid Surgery Trial (ECST) method [ 19 ]. The carotid total plaque area (cTPA) was used as an indicator of the carotid plaque burden using the measurement technique described earlier [ 20 , 21 ]. The burden of systemic atherosclerosis was assessed using the ultrasound atherosclerosis burden score (ABS) [ 22 ].…”

Section: Methodsmentioning

confidence: 99%

Liver Stiffness Is Associated with the Burden of Carotid and Systemic Atherosclerosis in an Unorganized Cohort of Patients 40–64 Years Old

et al. 2022

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Background: The aim of the study is to research the relationship between the severity of liver fibrosis and the burden of carotid and systemic atherosclerosis. Methods: The study includes 163 patients 40 to 64 years of age without atherosclerotic CVD or liver disease. All patients underwent duplex scanning of the carotid and lower limb arteries. All patients underwent transient liver elastometry using the FibroScan (Echosens, France). Results: Carotid plaque was detected in 110 (67.5%) patients. Based on the results of linear regression analysis, relationships between liver stiffness and carotid total plaque area (r = 0.21; p = 0.025) were found. Significant relationships were established between liver stiffness and atherosclerosis burden score based on the results of linear regression (r = 0.17; p = 0.029). Liver stiffness showed moderate diagnostic performance (AUC 0.666; p = 0.01) with regard to generalized atherosclerosis. An increase in liver stiffness >4.5 kPa was associated with an odds ratio of generalized atherosclerosis of 3.48 (95% CI 1.07–11.3; p = 0.038) after adjusting confounding factors. Conclusion: Among patients 40–64 years of age without established atherosclerotic CVD and liver disease, liver stiffness directly correlates with the burden of carotid and systemic atherosclerosis. Liver stiffness showed moderate diagnostic performance (AUC 0.666; p = 0.01) with regard to generalized atherosclerosis.

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“…Published by Francis Academic Press, UK -36-been reported that ankle-brachial index (ABI) ≤0.9 indicates atherosclerotic stenosis 9 . Increased Achilles tendon thickness (ATT) has also been found to be an independent predictor of carotid atherosclerosis 10 .…”

Section: Atherosclerotic Icasmentioning

confidence: 99%

Application of ultrasound in the evaluation of internal carotid artery stenosis

2023

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Internal carotid artery stenosis (ICAS) is one of the most important factors leading to ischemic stroke due to various etiologies. The choice of clinical individualized treatment plan varies according to the severity of the lesion. With the continuous improvement of current diagnosis and treatment standards, higher demands are placed on the evaluation of ultrasonic imaging characteristics of ICAS. Ultrasound can not only identify the etiology of ICAS, grade the severity of stenosis, and evaluate cerebral blood perfusion, but also conduct long-term follow-up to evaluate treatment effectiveness and the control of risk factors. Accurate classification and evaluation of ICAS lesions by ultrasound imaging provide scientific and reliable objective information for clinical diagnosis and treatment, thereby assisting in the selection of clinical individualized treatment. Therefore, this article reviews the clinical application and progress of ultrasound in the evaluation of ICAS.

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Achilles Tendon Thickness Is an Independent Predictor of Carotid Atherosclerosis and Is Associated With a Carotid Plaque Burden

Cited by 6 publications

References 24 publications

Achilles tendon thickness normalized to body surface area as a marker of asymptomatic peripheral arterial disease

Achilles tendon thickness normalized to body surface area as a marker of asymptomatic peripheral arterial disease

Liver Stiffness Is Associated with the Burden of Carotid and Systemic Atherosclerosis in an Unorganized Cohort of Patients 40–64 Years Old

Application of ultrasound in the evaluation of internal carotid artery stenosis

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