Achieving high mechanical properties of biodegradable vascular stents by four-axis 3D printing system and heat treatment

Tong, Xingrui; Zhang, Zhongsen; Fu, Kunkun; Li, Yan; Cao, Bingyan; Wang, Wenzhao; Chen, Biqiong

doi:10.1016/j.matlet.2023.134261

Cited by 3 publications

(4 citation statements)

References 8 publications

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“…It has been observed that the sharp edges of stents produced via the traditional FDM process can cause damage to the vessels. Additionally, it can cause stress concentration within the structure that can have negative effects on the patient vessels [ 46 ]. It was shown that FDM printed parts exhibit superior tribological characteristics along the fiber printing direction when compared both to direction transverse to a printed fibers direction and to a layer stacking direction [ 56 ].…”

Section: Resultsmentioning

confidence: 99%

“…Novel studies have found alternative, bioabsorbable and biodegradable vascular stents (BVS) due to their ability to provide support over a predefined amount of time, before they are reabsorbed within the vessel, removing the need for further surgery [ 43 ]. In general, PLA based stents have received a great deal of attention, due to being fully biocompatible for human use [ 10 , 35 , 44 , 45 , 46 ]. As previously stated, the main BVS advantage over BMS is that it does not corrode, whereas BMS corrosion can further provoke atherosclerosis and potential inflammatory response due to toxicity of the metallic ions.…”

Section: Introductionmentioning

confidence: 99%

“…Biodegradable vascular scaffolds, as radially loaded structures, bear load on their walls, and their improvement can achieved in layer-by-layer printing, in a cylindrical coordinate system. For this purpose, we have created a special four-axis printing system with a similar concept as in [ 37 , 46 , 55 ]. As the structure of the biodegradable stents mainly assumes cylindrical supporting structures, the standard layer-by-layer manufacturing method did not provide adequate mechanical characteristics, except in the case of test prototypes [ 53 ].…”

Section: Introductionmentioning

confidence: 99%

“…To the best of our knowledge, although specific elements has been used, there is no study where all of these elements are jointly applied to create the scaffolds by using four-axis printing [ 37 , 46 , 55 ] of smart materials through the 4D printing process. In this paper, a novel method of printing and testing of the 4D printed PLA biomedical devices is presented, in particular related to the biodegradable vascular stents (BVS).…”

Section: Introductionmentioning

confidence: 99%

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Thermo-Mechanical Characterization of 4D-Printed Biodegradable Shape-Memory Scaffolds Using Four-Axis 3D-Printing System

et al. 2023

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This study was conducted on different models of biodegradable SMP (shape-memory polymer) scaffolds. A comparison was conducted utilizing a basic FDM (fused deposition modeling)/MEX (material extrusion) printer with a standard printing technique and a novel, modified, four-axis printing method with a PLA (poly lactic acid) polymer as the printing material. This way of making the 4D-printed BVS (biodegradable vascular stent) made it possible to achieve high-quality surfaces due to the difference in printing directions and improved mechanical properties—tensile testing showed a doubling in the elongation at break when using the four-axis-printed specimen compared to the regular printing, of 8.15 mm and 3.92 mm, respectfully. Furthermore, the supports created using this method exhibited a significant level of shape recovery following thermomechanical programming. In order to test the shape-memory effect, after the thermomechanical programming, two approaches were applied: one approach was to heat up the specimen after unloading it inside temperature chamber, and the other was to heat it in a warm bath. Both approaches led to an average recovery of the original height of 99.7%, while the in-chamber recovery time was longer (120 s) than the warm-bath recovery (~3 s) due to the more direct specimen heating in the latter case. This shows that 4D printing using the newly proposed four-axis printing is an effective, promising technique that can be used in the future to make biodegradable structures from SMP.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Thermo-Mechanical Characterization of 4D-Printed Biodegradable Shape-Memory Scaffolds Using Four-Axis 3D-Printing System

et al. 2023

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Review of recent progress in vascular stents: From conventional to functional vascular stents

Li,

Hu,

Chen

et al. 2024

Chinese Chemical Letters

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Mechanical Property of Thermoplastic Polyurethane Vascular Stents Fabricated by Fused Filament Fabrication

Zhai,

Sun,

Zhang

et al. 2024

Micromachines

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Vascular stents have many applications in treating arterial stenosis and other vascular-related diseases. The ideal vascular stent for clinical application should have radial support and axial bending mechanical properties that meet the requirements of vascular deformation coordination. The materials used for vascular stents implanted in the human body should have corresponding biocompatibility to ensure that the stents do not cause coagulation, hemolysis, and other reactions in the blood. This study fabricated four types of vascular stents, including inner hexagon, arrowhead, quadrilateral, and outer hexagonal, using fused filament fabrication technology and thermoplastic polyurethane (TPU) as materials. By evaluating the effects of edge width and wall thickness on the radial support and axial bending performance, it was found that the inner hexagonal stent exhibited the best radial support and axial bending performance under the same conditions. The design and fabrication of vascular stents based on 3D printing technology have promising application prospects in personalized customized vascular repair therapy.

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Achieving high mechanical properties of biodegradable vascular stents by four-axis 3D printing system and heat treatment

Cited by 3 publications

References 8 publications

Thermo-Mechanical Characterization of 4D-Printed Biodegradable Shape-Memory Scaffolds Using Four-Axis 3D-Printing System

Thermo-Mechanical Characterization of 4D-Printed Biodegradable Shape-Memory Scaffolds Using Four-Axis 3D-Printing System

Review of recent progress in vascular stents: From conventional to functional vascular stents

Mechanical Property of Thermoplastic Polyurethane Vascular Stents Fabricated by Fused Filament Fabrication

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