Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry
Alireza Kavand,
Perrine Robin,
Lucas Mayoraz
et al.
Abstract:Surface functionalization of glass involving peptide-based branched spacer and click chemistry allows for efficient covalent conjugation of single-strand DNA to achieve high hybridization density tailored for biosensing applications.
The fundamentals of bio-orthogonal click chemistry are investigated, while exploring mechanistic intricacies, demonstrating the adaptability and promise of this methodology.
The fundamentals of bio-orthogonal click chemistry are investigated, while exploring mechanistic intricacies, demonstrating the adaptability and promise of this methodology.
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