Acetylshikonin induces necroptosis via the RIPK1/RIPK3-dependent pathway in lung cancer
Shih-Sen Lin,
Tsung-Ming Chang,
Augusta I-Chin Wei
et al.
Abstract:Despite advances in therapeutic strategies, lung cancer remains the leading cause of cancer-related death worldwide. Acetylshikonin is a derivative of the traditional Chinese medicine Zicao and presents a variety of anticancer properties. However, the effects of acetylshikonin on lung cancer have not been fully understood yet. This study explored the mechanisms underlying acetylshikonin-induced cell death in non-small cell lung cancer (NSCLC). Treating NSCLC cells with acetylshikonin significantly reduced cell… Show more
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