Acetylcholine as a catalyst of hydroperoxide decomposition to free radicals

Krugovov, D. A.; Mengele, E. A.; Касаикина, О. Т.

doi:10.1007/s11172-014-0673-9

Cited by 15 publications

(3 citation statements)

References 13 publications

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“…Hydroperoxides may even decompose into toxic substances such as malonaldehyde (MDA) and 4-hydroxynonenal (HNE). During the chain transfer period, the free radicals generated by the decomposition of the hydroperoxides can react with unoxidized oil, continuously creating new free radicals and hydroperoxides to accelerate the oxidation of oil (Krugovov et al, 2014).…”

Section: Restraining the Formation And Reactivity Of Hydroperoxidementioning

confidence: 99%

Review on preparation methods, mechanisms and applications for antioxidant peptides in oil

Pan

Yang

et al. 2022

grasasaceites

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Natural antioxidants, especially those used in edible oil, are safer compared to chemically synthesized antioxidants. Therefore, research on natural antioxidants has become prevelant. Antioxidant peptides derived from food protein can effectively prevent oil oxidation. Protein hydrolyzation is widely applied for the production of antioxidant peptides in industry, and bioinformatics is employed nowadays to generate the desired peptide sequence. Furthermore, the mechanism of antioxidant peptides in the oil system is still controversial, which limits the further development of antioxidant peptides as food antioxidants. This review introduces the preparation method of antioxidant peptides and their mechanisms as well as applications in the oil. It will help to comprehensively understand the function of antioxidant peptides and promote their development in the oil field.

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Section: Restraining the Formation And Reactivity Of Hydroperoxidementioning

confidence: 99%

Review on preparation methods, mechanisms and applications for antioxidant peptides in oil

Pan

Yang

et al. 2022

grasasaceites

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show abstract

“…(2) The comparison of the effects of different surfactants on lipid and hydrocarbon oxidation reveals that cationic surfactants (S + ) promote hydroperoxide destruction resulting in the formation of free radicals and thus S + accelerate the oxidation as a whole . It must be noted that in organic solvents, the well‐known neuromediator acetylcholine (ACh) forms mixed micelles {mLOOH…nACh}, accelerates lipid oxidation and hydroperoxide decomposition into free radicals similarly to cationic surfactants . Mixed micelles are, as a matter of fact, self‐organized nanoreactors in which active polar substances such as LOOH, metal compounds, phenols, amines, etc.…”

Section: Micellar Effects In Liquid‐phase Oxidationmentioning

confidence: 99%

Unusual antioxidant effects in multiphase and complex systems

Касаикина

Krugovov

Mengele

2017

Euro J Lipid Sci & Tech

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In recent years, a number of studies have produced evidence that the multiphase and boundary effects in the systems containing surfactants, have to be taken into account for the development of innovative antioxidant technologies of lipid containing products. This report presents some unusual antioxidant effects, which occur only in multiphase complex systems due to the influence of surfactants (S).Hydroperoxides (LOOH), the primary oxidation products, form mixed micelles with surfactants (S) {nLOOHmS}. In the case of cationic surfactants (S + ), an accelerated hydroperoxide decomposition resulted in free radical generation occurs. Moderate magnetic field affects the free radical escape from mixed micelles {nLOOHmS + } into bulk solution; it can result in inhibiting of lipid oxidation in micellar system. Nonionic S can inhibit the catalyzed lipid oxidation by solubilization of the hydrophilic catalyst and spatial separation of the catalyst and substrate. Anionic surfactants alkylsulfates and alkylphosphates are effective antioxidants for alkylaromatic hydrocarbons due to the catalytic heterolytic decomposition of hydroperoxides into carbonyl compound and phenol which scavenges peroxyl radicals.

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“…Since the hydroperoxyl groups of hydroperoxides formed during lipid oxidation tend to be in the aqueous phase, thus forming mixed micelles. In this case, some cationic surfactants (CTAB, CTAC) can act as catalysts for the decomposition of hydroperoxides, [12][13][14] which leads to additional initiation. This effect can be associated with the formation of a Stern layer at the interface.…”

Section: Introductionmentioning

confidence: 99%

Oxidation of Methyl Linoleate in Triton X‐100 Micelles Initiated by Lipid‐soluble Initiator 2,2′‐Azobis (2,4‐dimethylvaleronitrile)

2023

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This article discusses the oxidation of methyl linoleate in micelles, initiated by the lipid-soluble initiator 2,2'-azobis (2,4dimethylvaleronitrile) (AMVN). It was shown that the rate constant (k i ) is initiated in micelles for AMVN significantly lower than the known rate constant of initiation in true solutions. This can be explained by the reduced probability of AMVN radicals leaving the cage and an increase in the rate of chain termination between initiator radicals under conditions of low oxygen content. This conclusion was confirmed by quantum chemical calculations. Surprisingly, when determining the AMVN initiation rate constant for the consumption of nitroxyl radicals (> NO * ), the k i depends on the concentration > NO * , this is due to the dependence of the probability of the nitroxyl radical and initiator radicals in micelles meeting on their concentration. Upon initiation of AMVN, no hydroperoxyl radical is expelled.

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Acetylcholine as a catalyst of hydroperoxide decomposition to free radicals

Cited by 15 publications

References 13 publications

Review on preparation methods, mechanisms and applications for antioxidant peptides in oil

Review on preparation methods, mechanisms and applications for antioxidant peptides in oil

Unusual antioxidant effects in multiphase and complex systems

Oxidation of Methyl Linoleate in Triton X‐100 Micelles Initiated by Lipid‐soluble Initiator 2,2′‐Azobis (2,4‐dimethylvaleronitrile)

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