Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement

Malagola, R; Arrico, L.; Giannotti, Rossella; Pattavina, Luigi

doi:10.2147/dddt.s38324

Cited by 17 publications

(7 citation statements)

References 20 publications

(23 reference statements)

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“…Хориоидальный выпот может возникнуть в глазах с хронической ПЗУГ или после острого приступа как на фоне местного, так и системного применения ингибиторов карбангидразы. В литературе описано несколько таких случаев [32][33][34][35][36][37]. По данным Donmez и соавт., хориоидальная эффузия на фоне применения ингибиторов карбангидразы может развиться сразу на обоих глазах [38].…”

Section: влияние лекарственных препаратов на толщину хориоидеиunclassified

The Role of Optical Coherence Tomography in the Diagnosis of Angle Closed Diseases of the Anterior Chamber. Part 2: Visualization of the Posterior Segment of the Eye

Курышева

Шарова

2021

Oftalʹmologiâ

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The purpose of this work is to review the literature data on the role of optical coherence tomography in the diagnosis of diseases of the closed angle of the anterior chamber. The analysis of the use of modern technical devices — optical coherence tomography of the posterior segment, models with a frequency-modulated source (Swept Source) is presented. The emergence of new imaging technologies such as SS-OCT contributes to understanding the pathogenesis of primary angle closure diseases in terms of involvement of the choroid in the process. A thicker choroid in the macular area may be an anatomical risk factor for closed angle disease. The expansion of an abnormally thick choroid in combination with the structural features of the anterior segment in eyes with a short axial length, including against the background of psychoemotional stress, can lead to an attack of angle closure. Visualization of the structures of the posterior segment of the eye is an important part of the strategy aimed at solving the problem of identifying risk factors, diagnosing, monitoring and evaluating the effectiveness of treatment of diseases of primary angle closure. Qualitative and quantitative data analysis based on optical coherence tomography significantly increases the diagnostic accuracy, allows to determine its progression and to predict its course. This plays a key role in the choice of treatment tactics for the anterior chamber angle closure. The review considers the effect of local antihypertensive eye drops on the choroid.Conclusion. Optical coherence tomography is a standard in modern diagnostics and evaluation of the effectiveness of treatment of diseases of primary angle closure, allowing a better understanding of the pathogenesis of the disease and its complex nature. Imaging improves the ability to accurately diagnose and choose the right treatment strategy.

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Section: влияние лекарственных препаратов на толщину хориоидеиunclassified

The Role of Optical Coherence Tomography in the Diagnosis of Angle Closed Diseases of the Anterior Chamber. Part 2: Visualization of the Posterior Segment of the Eye

Курышева

Шарова

2021

Oftalʹmologiâ

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“…Besides topiramate, other sulfonamides have been reported to cause a similar clinical syndrome, including acetazolamide [9], sulfasalazine [10], hydrochlorothiazide [10], and indapamide [4,11]. All ocular findings are reversible if recognized early and the drug is discontinued.…”

Section: Introductionmentioning

confidence: 99%

“…Most common ocular signs of acute ACG from topiramate include abnormal vision, acute intraocular pressure elevation, acute myopia [ 6 ], microcystic corneal edema, shallow anterior chamber [ 1 ], circumciliary congestion, retinal striae [ 7 ], macular folds, choroidal detachments, and ciliochroidal detachments [ 8 ]. Besides topiramate, other sulfonamides have been reported to cause a similar clinical syndrome, including acetazolamide [ 9 ], sulfasalazine [ 10 ], hydrochlorothiazide [ 10 ], and indapamide [ 4 , 11 ]. All ocular findings are reversible if recognized early and the drug is discontinued.…”

Section: Introductionmentioning

confidence: 99%

Acute myopia and angle closure glaucoma from topiramate in a seven-year-old: a case report and review of the literature

et al. 2014

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BackgroundA case is reported of acute bilateral myopia and angle closure glaucoma in a 7-year-old patient from topiramate toxicity. This is the second known reported case of topiramate induced acute angle closure glaucoma and third known reported case of topiramate induced acute myopia in a pediatric patient.Case presentationThis case presents a 7-year-old who had recently begun topiramate therapy for seizures and headache. She developed painless blurred vision and acute bilateral myopia, which progressed to acute bilateral angle closure glaucoma. After a routine eye exam where myopia was diagnosed, the patient presented to the emergency room with symptoms of acute onset blurry vision, tearing, red eyes, swollen eyelids, and photophobia. The symptoms, myopia, and angle closure resolved with topical and oral intraocular pressure lowering medications, topical cyclopentolate, and discontinuation of topiramate.ConclusionAcute angle closure glaucoma is a well-known side effect of topiramate, but is rarely seen in children. It cautions providers to the potential ophthalmic side effects of commonly used medications in the pediatric population. It highlights the need to keep a broad differential in mind when encountering sudden onset blurry vision in the primary care clinic, the need for careful consideration of side effects when starting topiramate therapy in a child, and the need for parental counseling of side effects.

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“…Treatment options include systematic drug withdrawal associated with cycloplegia, anti-glaucomatous agents, and/or corticosteroids. Full recovery is achieved within about 5 days (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14). Given the widespread use of acetazolamide, awareness of this idiosyncratic reaction is crucial to avoid complications of acute angle-closure glaucoma.…”

mentioning

confidence: 99%

Acute Myopic Shift after a Single Dose of Acetazolamide: A Case Report and Review of the Literature

Kaisari,

Abouzeid,

Magnin

et al. 2024

Klin Monbl Augenheilkd

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We report the case of a 32-year-old male who presented with an acute myopic shift as a result of uveal effusion following a single administration of 250 mg acetazolamide. The drug was discontinued and following cycloplegia and topical steroid therapy, we observed progressive deepening of the anterior chamber, reopening of the iridocorneal angle, and complete resolution of the myopic shift after 5 days. A literature review since 1956 identified 23 cases, including ours, which developed a myopic shift after a median time of 24 h (3 – 24) following a median dose of 500 mg (125 – 1000) acetazolamide, with about a third complicated by angle closure ocular hypertension. This presumed idiosyncratic reaction can occur without prior drug exposure and independent of the phakic status. Treatment options include systematic drug withdrawal associated with cycloplegia, anti-glaucomatous agents, and/or corticosteroids. Full recovery is achieved within about 5 days (2 – 14). Given the widespread use of acetazolamide, awareness of this idiosyncratic reaction is crucial to avoid complications of acute angle-closure glaucoma.

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Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement

Cited by 17 publications

References 20 publications

The Role of Optical Coherence Tomography in the Diagnosis of Angle Closed Diseases of the Anterior Chamber. Part 2: Visualization of the Posterior Segment of the Eye

The Role of Optical Coherence Tomography in the Diagnosis of Angle Closed Diseases of the Anterior Chamber. Part 2: Visualization of the Posterior Segment of the Eye

Acute myopia and angle closure glaucoma from topiramate in a seven-year-old: a case report and review of the literature

Acute Myopic Shift after a Single Dose of Acetazolamide: A Case Report and Review of the Literature

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