Acetazolamide for patients with acute decompensated heart failure with volume overload

Rosselló, Xavier; Menon, Venu; Vranckx, Pascal

doi:10.1093/ehjacc/zuac108

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…However, these treatments are often insufficient in significantly reducing rehospitalization rates and mortality, even when patients adhere to established guidelines ( Lai et al, 2022 ). Moreover, traditional medication can lead to adverse effects, including hypotension, hypokalemia, and renal function impairment ( Hubers and Brown, 2016 ; Marciniak and Serebruany, 2019 ; Rossello et al, 2022 ). Consequently, there is a pressing need to explore new therapeutic agents to enhance survival rates and improve the quality of life for HF patients.…”

Section: Pharmacological Action Of Rg3 In Heart Diseasesmentioning

confidence: 99%

The protective role of ginsenoside Rg3 in heart diseases and mental disorders

Shi,

Luo,

Wei

et al. 2024

Front. Pharmacol.

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Ginsenoside Rg3, a compound derived from Panax ginseng C. A. Mey., is increasingly recognized for its wide range of pharmacological effects. Under the worldwide healthcare challenges posed by heart diseases, Rg3 stands out as a key subject in modern research on Chinese herbal medicine, offering a novel approach to therapy. Mental illnesses are significant contributors to global disease mortality, and there is a well-established correlation between cardiac and psychiatric conditions. This connection is primarily due to dysfunctions in the sympathetic-adrenomedullary system (SAM), the hypothalamic-pituitary-adrenal axis, inflammation, oxidative stress, and brain-derived neurotrophic factor impairment. This review provides an in-depth analysis of Rg3’s therapeutic benefits and its pharmacological actions in treating cardiac and mental health disorders respectively. Highlighting its potential for the management of these conditions, Rg3 emerges as a promising, multifunctional therapeutic agent.

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