Acetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders

Liew, Zeyan; Ritz, Beate; Rebordosa, Cristina; Lee, Pei‐Chen; Olsen, Jørn

doi:10.1001/jamapediatrics.2013.4914

Cited by 311 publications

(322 citation statements)

References 34 publications

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“…50 Although acetaminophen has long been considered safe for use in pregnancy, a new study has linked its use in pregnancy to risk of attention deficit hyperactivity disorder (ADHD), where the effect appears to be related to quantity of acetaminophen used. 51 Both NSAIDs and triptans are safe in lactation, with the recommendation that women should pump 2-4 hours following triptan ingestion and discard the milk. 52 The two safest preventives in pregnancy include biofeedback and nerve blocks.…”

Section: Treatmentmentioning

confidence: 99%

Headache in the Emergency Room

Kahkeshani¹,

Sheikh²

2017

US Endocrinology

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Headache is seen in the emergency room (ER) on a daily basis and is a vague symptom, which can be a part of many different types of conditions and diseases. Although most people who come to the ER will have a benign headache, it is important to make sure that dangerous causes of headache are ruled out. There are a number of features that may alert someone to a secondary cause of headache. This article highlights two specific secondary headache syndromes, including carotid dissection and reversible cerebral vasoconstriction syndrome. It also broadly points out other possible causes of secondary headache. The last section focuses on a common primary headache that presents to the ER, migraine and its treatment.

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Section: Treatmentmentioning

confidence: 99%

Headache in the Emergency Room

Kahkeshani¹,

Sheikh²

2017

US Endocrinology

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“…Der er naeppe tvivl om at vi bør undersøge mange flere praeparater for føtal programmeringseffekt -ikke blot medfødte misdannelser. Erfaring fra studier af paracetamol (21)(22)(23)(24)(25) viser, at vi også skal interessere os for helt andre udfald. Dette praeparat anses af mange for sikkert at bruge -også for gravide -men det er måske ikke rigtigt.…”

Section: Nye Forskningområderunclassified

Løbende nationale reproduktionsregistre og ad hoc data

Olsen

2017

Nor J Epidemiol

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ENGLISH SUMMARYOlsen J. National registration in human reproduction and research oriented ad hoc data. Nor J Epidemiol 2017; 27 (1-2): 27-31.The Nordic countries have a long tradition for collecting and storing of data in reproductive health. These registers cover the entire population and focus on health outcomes. They have gradually been made available for research and if supplemented with data on potential risk factors in reproductive health, they provide a strong basis for research in potential causes of disease in the reproductive system. Several pregnany/birth cohorts have been successful in providing important information in preventive medicine. The most important of these are the Norwegian birth cohort (MoBa) and the Danish National Birth Cohort (DNBC). Both include about 100,000 newborns. They are based on the rationale that many diseases have causes that start operating in fetal life -fetal programming of diseases -even diseases that manifest themselves later in life (adult diseases). Examples of historic and more recent findings are presented in the following text. Risk of disclosure of personal data is of concern. We have not had examples of such unwanted disclosure and we want to keep this achievement. We clearly have to do many things different and better in the future. Fortunately, technical solutions are available and promising.The registers and the ad hoc data sources have given the Nordic epidemiologists a leading position in reproductive health. To keep that position, we need to plan new cohorts and train more people. If we do that we will be able to continue our collaboration with colleagues all over the world.This is an open access article distributed under the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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“…Using the same sources as in their study 5 described in the previous section, Liew et al 12 examined the association between prenatal acetaminophen exposure and a registry diagnosis of ADHD. Analyses were adjusted for a large number of potential demographic-, maternal-, paternal-, and child-derived confounds, including those related to pain, fever, infection, and inflammation (however, family history of ADHD was not adjusted for).…”

Section: Prenatal Acetaminophen Exposure and Adhdmentioning

confidence: 99%