Acetaminophen Overdose as a Suicidal Gesture: A Survey of Adolescents' Knowledge of Its Potential for Toxicity

Abstract

Acetaminophen is a popular nonprescription analgesic that is often taken in overdose by adolescents during suicidal gestures. The authors hypothesized that most adolescents are naive about the toxic and lethal potential of acetaminophen in overdose. A one-page, 12-item questionnaire was administered to 169 high school students to evaluate their perceptions and knowledge in this area. Whereas only 22% of the sample underestimated the dose of acetaminophen necessary to cause harm, 40.5% underestimated the potential lethality of acetaminophen in overdose. Moreover, 17% of the sample did not believe one could ingest enough acetaminophen to cause death. The lack of knowledge about acetaminophen's potential dangerousness, its widespread availability, and an absence of early symptoms of hepatotoxicity make this medication highly dangerous to those adolescents who take it in overdose during parasuicidal behavior.

Characteristics of children and adolescents presenting to the emergency department with self-inflicted injury: Retrospective analysis of two teaching hospitals

“…The increase in poisoning is noteworthy as the long-term consequences of cardiac and hepatic toxicity may not be appreciated by youths. 28 Besides confirming patients with schizophrenia and mood disorders having increased risk of repeated selfinflicted injuries as reported in other studies, 16,20,29 our findings also showed a higher proportion of children with previous self-harm having multiple psychiatric diagnoses compared with children without a history of self-inflicted injury. A strong doseeresponse relationship between the number of mental health disorders and risk of subsequent suicide attempt had been demonstrated.…”