Acetaminophen, Aspirin, and Chronic Renal Failure

Fored, C. Michael; Ejerblad, Elisabeth; Lindblad, Per; Fryzek, Jon P.; Dickman, Paul W.; Signorello, Lisa B.; Lipworth, Loren; Elinder, Carl‐Gustaf; Blot, William J.; McLaughlin, Joseph K.; Zack, M. M.; Nyrén, Olof

doi:10.1056/nejmoa010323

Cited by 246 publications

(148 citation statements)

References 194 publications

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“…Dotyczy to również stosowania uważanego za mniej szkodliwy paracetamolu. Dlatego preferowanymi środkami przeciwbólowymi w niewydolności krążenia są opioidy oraz metamizol [55][56][57]. Szczególnie dużym ryzykiem obciążeni są chorzy przyjmujący jednocześnie ACEI i diuretyki oraz chorzy na cukrzycę [58].…”

Section: Metody Farmakologiczneunclassified

Postępowanie w okresie okołooperacyjnym u chorych z ryzykiem wystąpienia ostrego uszkodzenia nerek, poddawanych operacjom kardiochirurgicznym

Krzych

Wybraniec²,

Chudek³

et al. 2013

Anaesthesiol Intensive Ther

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Acute kidney injury is one of the most frequent and clinically important of all postoperative complications in cardiac surgery. It is estimated that almost half of subjects suffer from a deterioration of kidney function after a cardio-pulmonary by-pass. Renal insufficiency impacts upon the outcome in terms of an increase in postoperative morbidity and mortality, and a decrease in quality of life. Recently, a modified and unified classification of cardio-renal syndrome has been devised, which takes into account bilateral association between the heart and the kidneys. Because acute decompensation in heart function leads to acute kidney damage, therefore cardiac surgery-associated acute kidney injury may be recognised as a type 1 cardio-renal syndrome from a pathophysiological point of view. This paper aims to review the current data on the diagnosis of acute kidney injury and preventive strategies that can be implemented in cardiac surgery perioperative care.

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Section: Metody Farmakologiczneunclassified

Postępowanie w okresie okołooperacyjnym u chorych z ryzykiem wystąpienia ostrego uszkodzenia nerek, poddawanych operacjom kardiochirurgicznym

Krzych

Wybraniec²,

Chudek³

et al. 2013

Anaesthesiol Intensive Ther

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“…88 Where studies have suggested a link between CKD and NSAID use, the risk appears to be low, and may be exacerbated by heavy use of one or more NSAIDs. 85,88,89 Two retrospective studies evaluated the safety of NSAIDs in a total of 76 older cats, including some cats with stable CKD. In both studies, cats received oral meloxicam (approximately 0.02 mg/kg/day) on a long-term basis for osteoarthritis.…”

Section: S P E C I a L A R T I C L E / Isfm/aafp Guidelines On Nsaidsmentioning

confidence: 99%

ISFM and AAFP Consensus Guidelines: Long-Term use of NSAIDs in Cats

Sparkes

Heiene

Lascelles

et al. 2010

Journal of Feline Medicine and Surgery

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NSAIDs and cats Non-steroidal anti-inflammatory drugs (NSAIDs) are an important class of drug in feline medicine, having analgesic, anti-inflammatory and antipyretic activity. While most published data on their use in this species relate to short-term (often perioperative) therapy, there is increasing evidence of the value of these drugs in treating chronic pain in cats (for example, that associated with degenerative joint disease), and some NSAIDs have now become licensed for long-term use in cats in some geographies. Most of our knowledge of therapeutic mechanisms or adverse drug reactions associated with NSAIDs is extrapolated from work in other species, and there is a paucity of published data relating to cats. Guidelines These guidelines have been drawn together by an expert panel, which have reviewed the current literature on long-term NSAID use in cats and other species, and developed guidance on their use based on this information. The aim is to provide practical information for veterinarians to encourage appropriate NSAID therapy whenever cats will benefit from the use of these drugs.

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“…Taken together with the findings of García Rodríguez and Hernandez-Diaz (13), as well as recent reports of chronic nephrotoxicity (25), it is appropriate that we reexamine assumptions regarding the risk-to-benefit ratio that has favored the use of acetaminophen over NSAIDs, particularly in diseases such as OA.…”

Section: Hypothesis Generating Not Resolvingmentioning

confidence: 99%